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  4. Recombinant Mouse Uncharacterized protein C17orf85 homolog

Recombinant Mouse Uncharacterized protein C17orf85 homolog

  • 货号：
    CSB-YP806467MO
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 货号：
    CSB-EP806467MO
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 货号：
    CSB-EP806467MO-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 货号：
    CSB-BP806467MO
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 货号：
    CSB-MP806467MO
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    Ncbp3
  • Uniprot No.：
  • 别名：
    Ncbp3; Nuclear cap-binding protein subunit 3
  • 种属：
    Mus musculus (Mouse)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-615
  • 氨基酸序列
    MAAVRGLRVS VKAEAPAGPA LGLPSPEVES GLERGEPEPM EVEEGELEIV PVRRSLKELL PDTSRRYENK AGSFITGIDV TSKEAIEKKE QRAKRFHFRA EVNLAQRNVA LDRDMMKKAI PKVRLETIYI CGVDEMSTQD IFSYFKEYPP AHIEWLDDTS CNVVWLDEMT ATRALINMSS LPAQDKMRSR DASEDKSSEK NKKDKQEDSS DDDETEEGEV EDENSSDVEL DTLSQVEEES LLRNDLRPAN KLAKGNRLFM RFATKDDKKE LGAARRSQYY MKYGNPNYGG MKGILSNSWK RRYHSRRIQR DVIKKRALIG DDVGLTSYKH RHSGLVNVPE EPIEEEEEEE EEEEDQDMDA DDRVVVEYHE ELPGLKQPRE RSLSRRSSAS SSDSDEMDYD LELKMISTPS PKKSMKMTMY ADEVESQLKS IRNPMRADSI STSNIKNRIG NKLPPEKFAD VRHLLDEKRQ HSCPRPAVSS TKPDIRQRLG KRPYSPEKAF SSNQVVRREP SSDVHSRLGV PRQDVKGLYS DTRERKSGGL WTRLGSTPKT KEKNTKKVDH RASGAEEDDS ELQRAWGALI KEKEESRQKK SRLDSLPSLQ IEVSRESSSG SEAES
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Associates with NCBP1/CBP80 to form an alternative cap-binding complex (CBC) which plays a key role in mRNA export. NCBP3 serves as adapter protein linking the capped RNAs (m7GpppG-capped RNA) to NCBP1/CBP80. Unlike the conventional CBC with NCBP2 which binds both small nuclear RNA (snRNA) and messenger (mRNA) and is involved in their export from the nucleus, the alternative CBC with NCBP3 does not bind snRNA and associates only with mRNA thereby playing a role in only mRNA export. The alternative CBC is particularly important in cellular stress situations such as virus infections and the NCBP3 activity is critical to inhibit virus growth.
  • 基因功能参考文献：
    1. Study proposes the existence of an alternative cap-binding complex involving NCBP1 and NCBP3 that plays a key role in mRNA biogenesis. PMID: 26382858
  • 亚细胞定位：
    Nucleus. Cytoplasm.
  • 蛋白家族：
    NCBP3 family
  • 数据库链接：

    KEGG: mmu:66874

    STRING: 10090.ENSMUSP00000021135

    UniGene: Mm.41903