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Recombinant Mouse Uncharacterized methyltransferase WBSCR22 (Wbscr22)

  • 中文名称:
    Recombinant Mouse Uncharacterized methyltransferase WBSCR22(Wbscr22),Yeast
  • 货号:
    CSB-YP887468MO
  • 规格:
  • 来源:
    Yeast
  • 其他:
  • 中文名称:
    Recombinant Mouse Uncharacterized methyltransferase WBSCR22(Wbscr22),Yeast
  • 货号:
    CSB-EP887468MO
  • 规格:
  • 来源:
    E.coli
  • 其他:
  • 中文名称:
    Recombinant Mouse Uncharacterized methyltransferase WBSCR22(Wbscr22),Yeast
  • 货号:
    CSB-EP887468MO-B
  • 规格:
  • 来源:
    E.coli
  • 共轭:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名称:
    Recombinant Mouse Uncharacterized methyltransferase WBSCR22(Wbscr22),Yeast
  • 货号:
    CSB-BP887468MO
  • 规格:
  • 来源:
    Baculovirus
  • 其他:
  • 中文名称:
    Recombinant Mouse Uncharacterized methyltransferase WBSCR22(Wbscr22),Yeast
  • 货号:
    CSB-MP887468MO
  • 规格:
  • 来源:
    Mammalian cell
  • 其他:

产品详情

  • 纯度:
    >85% (SDS-PAGE)
  • 基因名:
    Bud23
  • Uniprot No.:
  • 别名:
    Bud23; Wbscr22Probable 18S rRNA; guanine-N(7))-methyltransferase; EC 2.1.1.-; Bud site selection protein 23 homolog; Williams-Beuren syndrome chromosomal region 22 protein homolog; rRNA methyltransferase and ribosome maturation factor
  • 种属:
    Mus musculus (Mouse)
  • 蛋白长度:
    full length protein
  • 表达区域:
    1-281
  • 氨基酸序列
    MASRSRRPEH SGPPELFYDQ NEARKYVRNS RMIDIQTKMT ERALELLCLP EGQPSYLLDI GCGSGLSGDY ISEEGHYWVG IDISPAMLDA ALDRDTEGDL LLGDMGQGVP FRPGSFDGCI SISAVQWLCN ANKKSDVPAR RLYCFFSSLY SALVRGARAV LQLYPENSEQ LELITTQATR AGFTGGVVVD FPNSAKAKKF YLCLFSGPST SLPKGLTESQ DADQASESMF TSERAPHKKA RRDLVKKSRE WVLEKKERRR RQGKEVRPDT QYTGRKRKPR F
  • 蛋白标签:
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

产品评价

靶点详情

  • 功能:
    S-adenosyl-L-methionine-dependent methyltransferase that specifically methylates the N(7) position of a guanine in 18S rRNA. Requires the methyltransferase adapter protein TRM112 for full rRNA methyltransferase activity. Involved in the pre-rRNA processing steps leading to small-subunit rRNA production independently of its RNA-modifying catalytic activity. Important for biogenesis end export of the 40S ribosomal subunit independent on its methyltransferase activity. Locus-specific steroid receptor coactivator. Potentiates transactivation by glucocorticoid (NR3C1), mineralocorticoid (NR3C2), androgen (AR) and progesterone (PGR) receptors. Required for the maintenance of open chromatin at the TSC22D3/GILZ locus to facilitate NR3C1 loading on the response elements. Required for maintenance of dimethylation on histone H3 'Lys-79' (H3K79me2), although direct histone methyltransferase activity is not observed in vitro.
  • 亚细胞定位:
    Nucleus. Nucleus, nucleoplasm. Cytoplasm, perinuclear region. Cytoplasm.
  • 蛋白家族:
    Class I-like SAM-binding methyltransferase superfamily, BUD23/WBSCR22 family
  • 数据库链接:

    KEGG: mmu:66138

    STRING: 10090.ENSMUSP00000083146

    UniGene: Mm.439878