Your Good Partner in Biology Research

  1. 首页
  2. 蛋白
  3. 重组蛋白
  4. Recombinant Mouse Tubulointerstitial nephritis antigen-like (Tinagl1)

Recombinant Mouse Tubulointerstitial nephritis antigen-like (Tinagl1)

  • 中文名称：
    小鼠Tinagl1重组蛋白
  • 货号：
    CSB-YP858743MO
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    小鼠Tinagl1重组蛋白
  • 货号：
    CSB-EP858743MO
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    小鼠Tinagl1重组蛋白
  • 货号：
    CSB-EP858743MO-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    小鼠Tinagl1重组蛋白
  • 货号：
    CSB-BP858743MO
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    小鼠Tinagl1重组蛋白
  • 货号：
    CSB-MP858743MO
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    Tinagl1
  • Uniprot No.：
  • 别名：
    Tinagl1; Arg1; Lcn7; Tinagl; Tubulointerstitial nephritis antigen-like; Adrenocortical zonation factor 1; AZ-1; Androgen-regulated gene 1 protein; Tubulointerstitial nephritis antigen-related protein; TARP
  • 种属：
    Mus musculus (Mouse)
  • 蛋白长度：
    Full Length of Mature Protein
  • 表达区域：
    22-466
  • 氨基酸序列
    RRSRWRREL APGLHLRGIR DAGGRYCQEQ DMCCRGRADE CALPYLGATC YCDLFCNRTV SDCCPDFWDF CLGIPPPFPP VQGCMHGGRI YPVFGTYWDN CNRCTCHEGG HWECDQEPCL VDPDMIKAIN RGNYGWQAGN HSAFWGMTLD EGIRYRLGTI RPSSTVMNMN EIYTVLGQGE VLPTAFEASE KWPNLIHEPL DQGNCAGSWA FSTAAVASDR VSIHSLGHMT PILSPQNLLS CDTHHQQGCR GGRLDGAWWF LRRRGVVSDN CYPFSGREQN EASPTPRCMM HSRAMGRGKR QATSRCPNGQ VDSNDIYQVT PAYRLGSDEK EIMKELMENG PVQALMEVHE DFFLYQRGIY SHTPVSQGRP EQYRRHGTHS VKITGWGEET LPDGRTIKYW TAANSWGPWW GERGHFRIVR GTNECDIETF VLGVWGRVGM EDMGHH
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    May be implicated in the adrenocortical zonation and in mechanisms for repressing the CYP11B1 gene expression in adrenocortical cells. This is a non catalytic peptidase C1 family protein.
  • 基因功能参考文献：
    1. Tinagl1 is related to fertility in adult females but is not essential for either fertilization or preimplantation development in vitro PMID: 26522507
    2. Data show that endothelial cell lines SVEC but not MB114 cells express low levels of endogenous LCN7 mRNA and that overexpression significantly increased LCN7 mRNA over basal levels in both cell lines. PMID: 21085487
    3. results suggest that tubulointerstitial nephritis antigen-like 1(Tinagl1) functions during the postimplantation period PMID: 19776386
    4. Collectively with the putative role of AZ-1 in the adrenocortical zonation, we propose that AZ-1 potentially regulates functions of adrenocortical and VSM cells by modulating cell-matrix interactions PMID: 17425658
    5. In mouse embryos, the expression of both Tinagl1 mRNA and TINAGL1 protein was increased just prior to implantation. During postimplantation, TINAGL1 expression was restricted to extraembryonic regions. PMID: 19587330

    显示更多

    收起更多

  • 亚细胞定位：
    Secreted.
  • 蛋白家族：
    Peptidase C1 family
  • 组织特异性：
    Highly expressed in kidney, heart and adrenocortical cells of adrenal glands. Moderately expressed in spleen and liver. Also found in prostate, seminal vesicle, epididymis and testis in male reproductive organs. In adrenal glands is found in the outer cor
  • 数据库链接：

    KEGG: mmu:94242

    STRING: 10090.ENSMUSP00000030560

    UniGene: Mm.15801