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  4. Recombinant Mouse Transcriptional repressor scratch 1 (Scrt1)

Recombinant Mouse Transcriptional repressor scratch 1 (Scrt1)

  • 中文名称：
    小鼠Scrt1重组蛋白
  • 货号：
    CSB-YP857497MO
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    小鼠Scrt1重组蛋白
  • 货号：
    CSB-EP857497MO
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    小鼠Scrt1重组蛋白
  • 货号：
    CSB-EP857497MO-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    小鼠Scrt1重组蛋白
  • 货号：
    CSB-BP857497MO
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    小鼠Scrt1重组蛋白
  • 货号：
    CSB-MP857497MO
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    Scrt1
  • Uniprot No.：
  • 别名：
    Scrt1; Transcriptional repressor scratch 1; Scratch homolog 1 zinc finger protein; SCRT; Scratch 1; mScrt
  • 种属：
    Mus musculus (Mouse)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-348
  • 氨基酸序列
    MPRSFLVKKV KLDTFSSADL DSSYGRARSD LGVRLQDKGY LSDYVGPASV YDGDAEAALL KGPSPEPMYA AAVRGELGPA ASGSAPPPTP RPELATAAGG YINGDAAVSE GYAADAFFIT DGRSRRKAAN ANAAAAPSTA SVAAPDSDAG GGGGPGTRGS GSGSASRGGT RVGAGTEARA GSGATGAGGR HACGECGKTY ATSSNLSRHK QTHRSLDSQL ARRCPTCGKV YVSMPAMAMH LLTHDLRHKC GVCGKAFSRP WLLQGHMRSH TGEKPFGCAH CGKAFADRSN LRAHMQTHSA FKHFQCKRCK KSFALKSYLN KHYESACFKG GASGPATPAP PQLSPVQA
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Transcriptional repressor that binds E-box motif CAGGTG. Appears to function downstream of proneural bHLH proteins in promoting neural differentiation.
  • 基因功能参考文献：
    1. Scratch proteins (1 and 2) mediate the conversion of neuroepithelial cells to migrating neurons through an epithelial-mesenchymal transition. PMID: 23434913
    2. SCRT1 transcripts are undetectable in nearly all of the examined tumors suggesting that SCRATCH1 plays a minor role, if any, in tumorigenesis. PMID: 20043117
    3. From perinatal to adult stages, Scratch1 remains strongly expressed in almost all brain regions, although it is not found in some ventral structures such as motor nuclei and hypothalamic regions. PMID: 16773660
  • 亚细胞定位：
    Nucleus.
  • 蛋白家族：
    Snail C2H2-type zinc-finger protein family
  • 数据库链接：

    KEGG: mmu:170729

    STRING: 10090.ENSMUSP00000094093

    UniGene: Mm.218747