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  4. Recombinant Mouse Sulfotransferase 1 family member D1 (Sult1d1)

Recombinant Mouse Sulfotransferase 1 family member D1 (Sult1d1)

  • 中文名称：
    小鼠Sult1d1重组蛋白
  • 货号：
    CSB-YP663693MO
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    小鼠Sult1d1重组蛋白
  • 货号：
    CSB-EP663693MO
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    小鼠Sult1d1重组蛋白
  • 货号：
    CSB-EP663693MO-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    小鼠Sult1d1重组蛋白
  • 货号：
    CSB-BP663693MO
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    小鼠Sult1d1重组蛋白
  • 货号：
    CSB-MP663693MO
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    Sult1d1
  • Uniprot No.：
  • 别名：
    Sult1d1; St1d1; Sulfotransferase 1 family member D1; ST1D1; EC 2.8.2.-; Amine N-sulfotransferase; SULT-N; Dopamine sulfotransferase Sult1d1; Tyrosine-ester sulfotransferase
  • 种属：
    Mus musculus (Mouse)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-295
  • 氨基酸序列
    MDNKLDVFRR ELVDVEGIPL FWSIAEHWSQ VESFEARPDD ILISTYPKSG TTWVSEILDL IYNNGDAEKC KRDAIYKRVP FMELIIPGIT NGVEMLNNMP SPRIVKTHLP VQLLPSSFWK NDCKIIYVAR NAKDVVVSYY YFYQMAKIHP EPGTWEEFLE KFMAGQVSFG PWYDHVKSWW EKRKEYRILY LFYEDMKENP KCEIQKILKF LEKDIPEEIL NKILYHSSFS VMKENPSANY TTMMKEEMDH SVSPFMRKGI SGDWKNQFTV AQYEKFEEDY VKKMEDSTLK FRSEI
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Sulfotransferase with broad substrate specificity that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfate conjugation of catecholamines, such as dopamine, prostaglandins, leukotriene E4, drugs and xenobiotic compounds. Has sulfotransferase activity towards p-nitrophenol, 2-naphthylamine and minoxidil (in vitro). Sulfonation increases the water solubility of most compounds, and therefore their renal excretion, but it can also result in bioactivation to form active metabolites.
  • 基因功能参考文献：
    1. Sult1d1 knockout did not influence furfuryl alcohol bioactivation or the formation of hemoglobin adducts. PMID: 29908303
    2. Sult1d1 in mice is directly induced by glucocorticoids and may attenuate elevated catecholamine activity during the stress response. PMID: 19966186
    3. Data obtained indicated that mSULT1D1 comprises of a single alpha/beta domain with a five-stranded parallel beta-sheet. PMID: 18977225
    4. The mechanism underlying the broad range substrate specificity of mSULT1D1 is proposed based on the two newly determined crystal structures. PMID: 19073143
    5. the crystal structure of mouse sulfotransferase, mSULT1D1, complexed with donor substrate 3'-phosphoadenosine 5'-phosphosulfate and accepter substrate p-nitrophenol was reported. PMID: 19344693
    6. active sites of PAPS-dependent SULT1D1 and phenolic sulfate-utilizing ASST represent an example of convergent evolution. PMID: 19695253

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  • 亚细胞定位：
    Cytoplasm.
  • 蛋白家族：
    Sulfotransferase 1 family
  • 组织特异性：
    Detected in kidney and liver. Detected in kidney collecting duct cells.
  • 数据库链接：

    KEGG: mmu:53315

    STRING: 10090.ENSMUSP00000108940

    UniGene: Mm.6824