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  4. Recombinant Mouse Sperm acrosome membrane-associated protein 3 (Spaca3), partial

Recombinant Mouse Sperm acrosome membrane-associated protein 3 (Spaca3), partial

  • 中文名称：
    小鼠Spaca3重组蛋白
  • 货号：
    CSB-YP880540MO
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    小鼠Spaca3重组蛋白
  • 货号：
    CSB-EP880540MO
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    小鼠Spaca3重组蛋白
  • 货号：
    CSB-EP880540MO-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    小鼠Spaca3重组蛋白
  • 货号：
    CSB-BP880540MO
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    小鼠Spaca3重组蛋白
  • 货号：
    CSB-MP880540MO
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    Spaca3
  • Uniprot No.：
  • 别名：
    Spaca3; Lyc3; Lyzl3; Sllp1; Sperm acrosome membrane-associated protein 3; Lysozyme-like protein 3; Sperm lysozyme-like protein 1; mSLLP1) [Cleaved into: Sperm acrosome membrane-associated protein 3; membrane form; Sperm acrosome membrane-associated protein 3; processed form]
  • 种属：
    Mus musculus (Mouse)
  • 蛋白长度：
    Partial
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Sperm surface membrane protein that may be involved in sperm-egg plasma membrane adhesion and fusion during fertilization. It could be a potential receptor for the egg oligosaccharide residue N-acetylglucosamine, which is present in the extracellular matrix over the egg plasma membrane. The processed form has no detectable bacteriolytic activity in vitro.
  • 基因功能参考文献：
    1. distinct from c-lysozyme by substituting two essential catalytic residues (E35T/D52N), and by forming helical filaments approximately 75 A in diameter with a 25 A central pore comprised of six monomers per helix turn repeating every 33 A PMID: 26198801
    2. Female mice immunized with SPRASA had profound infertility following timed matings and those mice that did become pregnant had reduced fetal viability. PMID: 25038051
    3. Data show that SAS1B/SAS1R (Sperm Acrosomal SLLP1 Binding/Sperm Acrosomal SLLP1 receptor) bound to sperm acrosomal protein SlLP1 with high affinity. PMID: 22206759
    4. This study demonstrates the retention of mouse sperm lysozyme-like protein (mSLLP1) in the equatorial segment of spermatozoa following the acrosome reaction and a role for mSLLP1 in sperm-egg binding and fertilization. PMID: 15982649
  • 亚细胞定位：
    Cytoplasmic vesicle, secretory vesicle, acrosome membrane; Single-pass type II membrane protein. Note=Anterior acrosome in non-capacitated spermatozoa and retained in the equatorial segment and in the luminal face of both the inner and outer acrosomal membranes following capacitation and the acrosome reaction.; [Isoform 2]: Secreted.
  • 蛋白家族：
    Glycosyl hydrolase 22 family
  • 组织特异性：
    The processed form is expressed in sperm (at protein level). Expressed strongly in testis and epididymis and weakly in pancreas.
  • 数据库链接：

    KEGG: mmu:75622

    STRING: 10090.ENSMUSP00000099511

    UniGene: Mm.26988