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  4. Recombinant Mouse Selenium-binding protein 1 (Selenbp1)

Recombinant Mouse Selenium-binding protein 1 (Selenbp1)

  • 中文名称：
    小鼠Selenbp1重组蛋白
  • 货号：
    CSB-YP020976MO
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    小鼠Selenbp1重组蛋白
  • 货号：
    CSB-EP020976MO
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    小鼠Selenbp1重组蛋白
  • 货号：
    CSB-EP020976MO-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    小鼠Selenbp1重组蛋白
  • 货号：
    CSB-BP020976MO
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    小鼠Selenbp1重组蛋白
  • 货号：
    CSB-MP020976MO
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
  • Uniprot No.：
  • 别名：
    Selenbp1; LpsbMethanethiol oxidase; MTO; EC 1.8.3.4; 56 kDa selenium-binding protein; SBP56; SP56; Selenium-binding protein 1
  • 种属：
    Mus musculus (Mouse)
  • 蛋白长度：
    Full Length of Mature Protein
  • 表达区域：
    2-472
  • 氨基酸序列
    ATKCTKCGP GYSTPLEAMK GPREEIVYLP CIYRNTGTEA PDYLATVDVD PKSPQYSQVI HRLPMPYLKD ELHHSGWNTC SSCFGDSTKS RNKLILPGLI SSRIYVVDVG SEPRAPKLHK VIEASEIQAK CNVSSLHTSH CLASGEVMVS TLGDLQGNGK GSFVLLDGET FEVKGTWEKP GDAAPMGYDF WYQPRHNVMV STEWAAPNVF KDGFNPAHVE AGLYGSRIFV WDWQRHEIIQ TLQMTDGLIP LEIRFLHDPS ATQGFVGCAL SSNIQRFYKN AEGTWSVEKV IQVPSKKVKG WMLPEMPGLI TDILLSLDDR FLYFSNWLHG DIRQYDISNP QKPRLAGQIF LGGSIVRGGS VQVLEDQELT CQPEPLVVKG KRIPGGPQMI QLSLDGKRLY ATTSLYSAWD KQFYPDLIRE GSMMLQIDVD TVNGGLKLNP NFLVDFGKEP LGPALAHELR YPGGDCSSDI WI
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Catalyzes the oxidation of methanethiol, an organosulfur compound known to be produced in substantial amounts by gut bacteria. Selenium-binding protein which may be involved in the sensing of reactive xenobiotics in the cytoplasm. May be involved in intra-Golgi protein transport.
  • 基因功能参考文献：
    1. These results have revealed a novel mechanism that SELENBP1-mediated cancer inhibition is through altering lipid/glucose metabolic signaling pathways. PMID: 25974208
    2. Selenbp1 suppresses the expression of tumor-promoting genes PMID: 23500078
    3. SBP1 has tumor suppressor functions that are inhibited in colorectal cancer through epigenetic silencing PMID: 19924303
  • 亚细胞定位：
    Nucleus. Cytoplasm, cytosol. Membrane; Peripheral membrane protein.
  • 蛋白家族：
    Selenium-binding protein family
  • 组织特异性：
    Highly expressed in liver, kidney and, to a lesser extent, lung.
  • 数据库链接：

    KEGG: mmu:20341

    STRING: 10090.ENSMUSP00000088349

    UniGene: Mm.196558