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  4. Recombinant Mouse Ribosyldihydronicotinamide dehydrogenase [quinone] (Nqo2)

Recombinant Mouse Ribosyldihydronicotinamide dehydrogenase [quinone] (Nqo2)

In Stock
  • 中文名称：
    小鼠Nqo2重组蛋白
  • 货号：
    CSB-YP881303MO
  • 规格：
    ￥1836
  • 图片：
    • (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
  • 其他：

产品详情

  • 纯度：
    Greater than 90% as determined by SDS-PAGE.
  • 基因名：
    Nqo2
  • Uniprot No.：
  • 别名：
    Nqo2; Nmor2; Ribosyldihydronicotinamide dehydrogenase [quinone]; EC 1.10.5.1; NRH dehydrogenase [quinone] 2; NRH:quinone oxidoreductase 2; Quinone reductase 2; QR2
  • 种属：
    Mus musculus (Mouse)
  • 蛋白长度：
    Full Length
  • 来源：
    Yeast
  • 分子量：
    28.2kDa
  • 表达区域：
    1-231aa
  • 氨基酸序列
    MAGKKVLIVYAHQEPKSFNGSLKKVAVEELSKQGCTVTVSDLYSMNFEPRATRNDITGAPSNPDVFSYGIETHEAYKKKALTSDIFEEQRKVQEADLVIFQFPLYWFSVPAILKGWMDRVLCRGFAFDIPGFYDSGFLKGKLALLSLTTGGTAEMYTKDGVSGDFRYFLWPLQHGTLHFCGFKVLAPQISFGLDVSSEEERKVMLASWAQRLKSIWKEEPIHCTPPWYFQE
    Note: The complete sequence including tag sequence, target protein sequence and linker sequence could be provided upon request.
  • 蛋白标签：
    N-terminal 6xHis-tagged
  • 产品提供形式：
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 缓冲液：
    Tris-based buffer,50% glycerol
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    3-7 business days
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet & COA：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    The enzyme apparently serves as a quinone reductase in connection with conjugation reactions of hydroquinones involved in detoxification pathways as well as in biosynthetic processes such as the vitamin K-dependent gamma-carboxylation of glutamate residues in prothrombin synthesis.
  • 基因功能参考文献：
    1. NQO2 stabilization of C/EBPalpha was independent of NQO1, even though both interacted with the same C/EBPa domain. PMID: 24142791
    2. Melatonin, acting at least partially via MT2 receptors, can regulate the redox status of quinone reductase II inhibited preadipocytes. PMID: 23554006
    3. role for NQO2 in protection against myelogenous hyperplasia and in metabolic activation of menadione, leading to hepatic toxicity PMID: 12351651
    4. These data establish dihydronicotinamide riboside:quinone reductase 2 (NQO2) as part of the MT3 binding site. PMID: 15581627
  • 亚细胞定位：
    Cytoplasm.
  • 蛋白家族：
    NAD(P)H dehydrogenase (quinone) family
  • 数据库链接：

    KEGG: mmu:18105

    STRING: 10090.ENSMUSP00000021843

    UniGene: Mm.264036