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  4. Recombinant Mouse Ribosomal RNA processing protein 1 homolog B (Rrp1b)

Recombinant Mouse Ribosomal RNA processing protein 1 homolog B (Rrp1b)

  • 中文名称：
    小鼠Rrp1b重组蛋白
  • 货号：
    CSB-YP821021MO
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    小鼠Rrp1b重组蛋白
  • 货号：
    CSB-EP821021MO
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    小鼠Rrp1b重组蛋白
  • 货号：
    CSB-EP821021MO-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    小鼠Rrp1b重组蛋白
  • 货号：
    CSB-BP821021MO
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    小鼠Rrp1b重组蛋白
  • 货号：
    CSB-MP821021MO
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    Rrp1b
  • Uniprot No.：
  • 别名：
    Rrp1b; Ribosomal RNA processing protein 1 homolog B; RRP1-like protein B
  • 种属：
    Mus musculus (Mouse)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-724
  • 氨基酸序列
    MALAMQSSEF QFAQRLASSE KGVRDRAVRK LRQYLSARTQ SDTGSFSQEE LLKIWKGLFY CMWVQDEPLL QEELANIISQ LIHVVNSLEA QYLFIQTFWQ TMNREWQGID KLQLDKYYML IRLVLRQSFE VLKRNAWEES QITLFLDILM KEILSPESQS PNGVRTHLID VYLEELTTVG GAELLADQNL KLIDPFCRIA AKTKDHTLVQ TVARGVFEVI VDQSACVPQE SVEERKTKED GSGFPTKALA CRKAVSGKKA ALDECLRDGV IGSRERDICA ALKDSGSPLQ FDYKAVADRL LEIANSKSTP PFNRKRLCRL VRKFQDLCEG NGAPLSSAED NGQRRHKRKR KKLLESEKGD TVSPAAEEDS GGHIHKKKRK KRKRSHFQPD TQNLDAVAVP KVPDSESEPD TAQRQAPCGQ ACVTEPTAEA VSSIGENSSK PTPVMPIHNK RKRPRKKKLR AHKEICKSTT LPQEDMSKND AVSGHSQSSA AHISSSEGVQ AQKRKRKLGA LPDSSSDLPV QKSGTPTSPV EGKDGQTTLP RCKRSQKKTA SSTLDPCDPS SQKPAISKKK KKTMKLMSNG VLESNPGQIQ ALGSNRTLKK PLKTEDDFVK FDTRFLPKPL FFRKAKNSSA TRPQGPAGQL NKTPSSSKKV TFGLNRNMTA EFKKTDKSIL VSPTGLSRVA FNPEQRPLHG VLKTATSSPA STPLSPMRLP ATTPKRRPRA ADFF
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Positively regulates DNA damage-induced apoptosis by acting as a transcriptional coactivator of proapoptotic target genes of the transcriptional activator E2F1. Likely to play a role in ribosome biogenesis by targeting serine/threonine protein phosphatase PP1 to the nucleolus. Involved in regulation of mRNA splicing. Inhibits SIPA1 GTPase activity. Involved in regulating expression of extracellular matrix genes. Associates with chromatin and may play a role in modulating chromatin structure.
  • 基因功能参考文献：
    1. RRP1B suppresses metastatic progression by altering the transcriptome through its interaction with splicing regulators such as SRSF1 PMID: 23604122
    2. RRP1B, a tumor progression and metastasis susceptibility candidate gene, is potentially a dynamic modulator of transcription and chromatin structure PMID: 19710015
  • 亚细胞定位：
    Nucleus, nucleolus. Nucleus, nucleoplasm. Chromosome.
  • 蛋白家族：
    RRP1 family
  • 数据库链接：

    KEGG: mmu:72462

    STRING: 10090.ENSMUSP00000080085

    UniGene: Mm.102761