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  4. Recombinant Mouse Rho GTPase-activating protein 36 (Arhgap36)

Recombinant Mouse Rho GTPase-activating protein 36 (Arhgap36)

  • 中文名称：
    Recombinant Mouse Rho GTPase-activating protein 36(Arhgap36),Yeast
  • 货号：
    CSB-YP532839MO
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    Recombinant Mouse Rho GTPase-activating protein 36(Arhgap36),Yeast
  • 货号：
    CSB-EP532839MO
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    Recombinant Mouse Rho GTPase-activating protein 36(Arhgap36),Yeast
  • 货号：
    CSB-EP532839MO-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    Recombinant Mouse Rho GTPase-activating protein 36(Arhgap36),Yeast
  • 货号：
    CSB-BP532839MO
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    Recombinant Mouse Rho GTPase-activating protein 36(Arhgap36),Yeast
  • 货号：
    CSB-MP532839MO
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    Arhgap36
  • Uniprot No.：
  • 别名：
    Arhgap36; Rho GTPase-activating protein 36
  • 种属：
    Mus musculus (Mouse)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-590
  • 氨基酸序列
    MAWMLDCLFA SAFEPRPRRV SVLGGAPGQN SDRSMDMVSI HSLSELERLK LQETAYHELV ARHFLSEFKP DRALPTDRPN TLEKWFLMLR GQDRAASLKT FGIRLEEVLV NELTRRKQRE LTPTMQVEDI NGSTGRRRRG NVVQRMLGRM RRFFSRRRNE PTLPREFTRR GRRGAVSADS ADELENGALL LQILQLSQLS SPIGQRLLGS KRKMSLNPIA QQIPQIVETC CKFIEKHGLS SVGIFTIEYS LRRVLELREL FDKGLDIVLD DSVNVHDVAE LLKEFFREMK DPLLPDDLYM SFLLTATLKP KDQVSALQLL VYLMPPCHSD TLERLLKALH KITENCEDSI GVDGQLVPGN RMTSTNLALV FGTALLKKGK LANKESRKTK LGIDHYVASV NVVRAMIDNW DILFQVPPHI QKEVAKRVWK SSPEALDFIR RRNLRKIQSA RIKMEEDALL SDPVENSAEA QAAILAQSQP FDEDPEGAPD VHEVLNDNLN YDFEDESDFE DQDHLDLAEV PYLDVIPNNE DTDSDADVIP GPSEEPAVPA STAGSPDKEE GAAGNPPNAD RPLPRVPQGK KGKFATRFFP
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state.
  • 基因功能参考文献：
    1. a new mechanism of Gli transcription factor activation and implicate ARHGAP36 dysregulation in the onset and/or progression of GLI-dependent cancers. PMID: 25024229
    2. Arhgap36 acts in a Smoothened-independent manner to promote the activation of full-length Gli proteins and induces the accumulation of Gli proteins in the primary cilium. Its ability to induce Gli-dependent transcription requires kinesin family member 3a and intraflagellar transport protein 88, proteins that are essential for ciliogenesis. Arhgap36 functionally and biochemically interacts with Suppressor of Fused. PMID: 25024229
  • 数据库链接：

    KEGG: mmu:75404

    STRING: 10090.ENSMUSP00000110554

    UniGene: Mm.44305