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  4. Recombinant Mouse Protein naked cuticle homolog 1 (Nkd1)

Recombinant Mouse Protein naked cuticle homolog 1 (Nkd1)

  • 中文名称：
    小鼠Nkd1重组蛋白
  • 货号：
    CSB-YP859149MO
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    小鼠Nkd1重组蛋白
  • 货号：
    CSB-EP859149MO
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    小鼠Nkd1重组蛋白
  • 货号：
    CSB-EP859149MO-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    小鼠Nkd1重组蛋白
  • 货号：
    CSB-BP859149MO
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    小鼠Nkd1重组蛋白
  • 货号：
    CSB-MP859149MO
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
  • Uniprot No.：
  • 别名：
    Nkd1; Protein naked cuticle homolog 1; Naked-1; mNkd; mNkd1
  • 种属：
    Mus musculus (Mouse)
  • 蛋白长度：
    Full Length of Mature Protein
  • 表达区域：
    2-471
  • 氨基酸序列
    GKLHSKPAA VCKRRESPEG DSFAVSAAWA RKGIEEWIGR QRCPGSVSGP RQLRLAGTVG RGTRELVGDT SREALGEEDE DDFPLEVALP PEKIDSLGSG DEKRMERLSE PGQASKKQLK FEELQCDVSV EEDSRQEWTF TLYDFDNNGK VTREDITSLL HTIYEVVDSS VNHSPTSSKT LRVKLTVAPD GSQSKRSVLF NHTDLQSTRP RADTKPAEEL RGWEKKQRAP LRFQGDSHLE QPDCYHHCVD ENIERRNHYL DLAGIENYTS QFGPGSPSVA QKSELPPRIS NPTRSRSHEP EAAHIPHRRP QGVDPGSFHL LDTPFAKASE LQQRLRGTQD GSKHFVRSPK AQGKNMGMGH GARGARSKPP LVPTTHTVSP SAHLATSPAL LPTLAPLGHK KHKHRAKESQ ASCRGLQGPL AAGGSTVMGR EQVRELPAVV VYESQAGQAV QRHEHHHHHE HHHHYHHFYQ P
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Cell autonomous antagonist of the canonical Wnt signaling pathway. May activate a second Wnt signaling pathway that controls planar cell polarity. Required for spermatogenesis.
  • 基因功能参考文献：
    1. The NKD1/Rac1 feedback loop regulates the invasion and migration ability of hepatocellular carcinoma cells. PMID: 27231134
    2. deletion of the EF-hand from Nkd1 reduces the number of the elongating spermatids at haploid stage PMID: 15546883
    3. Viable mice were obtained with compound mutations in the Wnt/Dvl pathway antagonists nkd1 and nkd2. PMID: 17438140
  • 亚细胞定位：
    Cell membrane. Cytoplasm.
  • 蛋白家族：
    NKD family
  • 组织特异性：
    Highly expressed in lung. Also expressed in brain, heart, kidney, liver, skin, stomach and testis. Within the testis expression is found in the seminiferous epithelium and round and elongating spermatids.
  • 数据库链接：

    KEGG: mmu:93960

    STRING: 10090.ENSMUSP00000034086

    UniGene: Mm.30219