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  4. Recombinant Mouse Protein BEX1 (Bex1)

Recombinant Mouse Protein BEX1 (Bex1)

  • 中文名称：
    Recombinant Mouse Protein BEX1(Bex1),Yeast
  • 货号：
    CSB-YP886443MO
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    Recombinant Mouse Protein BEX1(Bex1),Yeast
  • 货号：
    CSB-EP886443MO
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    Recombinant Mouse Protein BEX1(Bex1),Yeast
  • 货号：
    CSB-EP886443MO-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    Recombinant Mouse Protein BEX1(Bex1),Yeast
  • 货号：
    CSB-BP886443MO
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    Recombinant Mouse Protein BEX1(Bex1),Yeast
  • 货号：
    CSB-MP886443MO
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    Bex1
  • Uniprot No.：
  • 别名：
    Bex1; Rex3Protein BEX1; Brain-expressed X-linked protein 1 homolog; Reduced expression protein 3; REX-3
  • 种属：
    Mus musculus (Mouse)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-128
  • 氨基酸序列
    MESKDQGVKN LNMENDHQKK EEKEEKPQDT IRREPAVALT SEAGKNCAPR GGRRRFRVRQ PIAHYRWDLM QRVGEPQGRM REENVQRFGG DVRQLMEKLR ERQLSHSLRA VSTDPPHHDH HDEFCLMP
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Signaling adapter molecule involved in p75NTR/NGFR signaling. Plays a role in cell cycle progression and neuronal differentiation. Inhibits neuronal differentiation in response to nerve growth factor (NGF). May act as a link between the cell cycle and neurotrophic factor signaling, possibly by functioning as an upstream modulator of receptor signaling, coordinating biological responses to external signals with internal cellular states.
  • 基因功能参考文献：
    1. BEX1 functions as an mRNA-dependent effector that augments pathology-promoting gene expression during heart failure. PMID: 29192139
    2. These results elucidate a novel role of Bex1 in myogenesis through regulating myoblast fusion. PMID: 26586200
    3. Bex family members play important roles in the formation of protein network hubs. PMID: 25612294
    4. Bex1 protein is over-expressed as a result of peripheral axonal damage and antagonizes the axon outgrowth inhibitory effect of myelin-associated glycoprotein. PMID: 20731761
    5. Trophectoderm-specific expression of the X-linked Bex1/Rex3 gene in preimplantation stage mouse embryos. PMID: 11835573
    6. In situ hybridization demonstrates cellular co-localization of olfactory marker protein mRNA with mRNAs for Bex1, Bex2, and Bex3 in olfactory receptor neuronss in olfactory tissue of the mouse PMID: 12911636
    7. Bex3 may be required in target tissues for mitochondrial function at a distinct phase of the cellular growth cycle. PMID: 15563833
    8. Thus, our results provide the first evidence that Bex1-KO mice show altered muscle regeneration, and allow us to propose that the interaction of Bex1 with Ca(2+)/CaM may be involved in skeletal muscle regeneration. PMID: 17884015
    9. Bex1 and 2 have been characterized as interacting partners of the olfactory marker protein (OMP). Bex immunoreactivity (ir) was primarily localized to neuronal cells within several regions of the brain. PMID: 15861462

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  • 亚细胞定位：
    Nucleus. Cytoplasm. Note=Shuttles between the cytoplasm and the nucleus.
  • 蛋白家族：
    BEX family
  • 组织特异性：
    Primarily localized to neuronal cells within several regions of the brain, including the olfactory epithelium, bulb, peri/paraventricular nuclei, suprachiasmatic nucleus, arcuate nucleus, median eminence, lateral hypothalamic area, thalamus, hippocampus a
  • 数据库链接：

    KEGG: mmu:19716

    STRING: 10090.ENSMUSP00000060005

    UniGene: Mm.422943