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  4. Recombinant Mouse [Protein ADP-ribosylarginine] hydrolase (Adprh)

Recombinant Mouse [Protein ADP-ribosylarginine] hydrolase (Adprh)

  • 中文名称：
    Recombinant Mouse [Protein ADP-ribosylarginine] hydrolase(Adprh),Yeast
  • 货号：
    CSB-YP001381MO
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    Recombinant Mouse [Protein ADP-ribosylarginine] hydrolase(Adprh),Yeast
  • 货号：
    CSB-EP001381MO
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    Recombinant Mouse [Protein ADP-ribosylarginine] hydrolase(Adprh),Yeast
  • 货号：
    CSB-EP001381MO-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    Recombinant Mouse [Protein ADP-ribosylarginine] hydrolase(Adprh),Yeast
  • 货号：
    CSB-BP001381MO
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    Recombinant Mouse [Protein ADP-ribosylarginine] hydrolase(Adprh),Yeast
  • 货号：
    CSB-MP001381MO
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    Adprh
  • Uniprot No.：
  • 别名：
    Adprh; Arh1; [Protein ADP-ribosylarginine] hydrolase; ADP-ribosylarginine hydrolase; EC 3.2.2.19; ADP-ribose-L-arginine cleaving enzyme
  • 种属：
    Mus musculus (Mouse)
  • 蛋白长度：
    Full length protein
  • 表达区域：
    1-362
  • 氨基酸序列
    MGGGLIERYV AAMVLSAAGD TLGYFNGKWE FIRDGETIHQ QLAQMGDLEA IDVARWRVSD DTVMHLATAE ALMEAGQSPD LPRLYSLLAK HYRDCMGDMD GRAPGGACMQ NAMLLQPNRA DGYRIPFNSH EGGCGAAMRA MCIGLRFPHP SQLDLLIQVS IESGRMTHHH PTGYLGSLAS ALFTAYAVNG KSPWQWGKGL MEVLPEAKKY ITQSGYFVKE NLQHWSYFEK EWEKYLELRG ILDGNSAPVF PQPFGVKERD QFYIDVSYSG WGGSSGHDAP MIAYDALLAA GDSWKELAHR AFFHGGDSDS TAAIAGCWWG VMYGFKGVNP ANYEKLEYRQ RLEEAGRALY SLGSKEDPVL DP
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Specifically acts as a arginine mono-ADP-ribosylhydrolase by mediating the removal of mono-ADP-ribose attached to arginine residues on proteins.
  • 基因功能参考文献：
    1. ARH1(-/-) and ARH1(+/-) mice spontaneously develop lymphomas, adenocarcinomas, & metastases more frequently than wild-type. Proper control of protein ADP-ribosylation levels affected by ARH1 is essential for cancer suppression. PMID: 21697277
    2. ADP-ribosylarginine hydrolase promoter activity pattern and involvement of Sp transcription factors are consistent with prior observations of widespread hydrolase expression in mammalian tissues. PMID: 15893437
    3. Cholera toxin-catalyzed ADP-ribosylation of cell proteins can be counteracted by ADPRH, which could function as a modifier gene in disease. PMID: 17526733
  • 蛋白家族：
    ADP-ribosylglycohydrolase family
  • 数据库链接：

    KEGG: mmu:11544

    STRING: 10090.ENSMUSP00000002923

    UniGene: Mm.20047