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  4. Recombinant Mouse Probable E3 ubiquitin-protein ligase HECTD2 (Hectd2)

Recombinant Mouse Probable E3 ubiquitin-protein ligase HECTD2 (Hectd2)

  • 中文名称：
    小鼠Hectd2重组蛋白
  • 货号：
    CSB-YP807492MO
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    小鼠Hectd2重组蛋白
  • 货号：
    CSB-EP807492MO
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    小鼠Hectd2重组蛋白
  • 货号：
    CSB-EP807492MO-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    小鼠Hectd2重组蛋白
  • 货号：
    CSB-BP807492MO
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    小鼠Hectd2重组蛋白
  • 货号：
    CSB-MP807492MO
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    Hectd2
  • Uniprot No.：
  • 别名：
    Hectd2; Probable E3 ubiquitin-protein ligase HECTD2; EC 2.3.2.26; HECT domain-containing protein 2; HECT-type E3 ubiquitin transferase HECTD2
  • 种属：
    Mus musculus (Mouse)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-774
  • 氨基酸序列
    MSEAARDLSP GAPPAVAAAA PEERKGKEPE REKLPPIVTA GAAAGLDRGS KGQISTFSSF VSTVTQKKEA AENRSSPTHL ALPNIRNVRD LPPICLDVRQ KQRMSVEALP SEVKVPPLPE PSLPSQPKTV KDFEEDLEKA EATGNWKTVH AFYITAFDSF TELNTAFKKD ATASFNTIED SGLNANLVNA VFDALLNTPQ DIQKSVLKGI INSLLQEWKG PRTKDDLRAY FILLQNPQFN ITSTYVIYAH LLRQIATLVE ADHHFLVHWL KKLSQKKFKQ LVERLLQFVS LRLFPAKPEE FPPLTKCTWW IPSAAKVLAL LNTANNLVHP PLVPYTDFYN STLDHIDLME EYHTWQSFGN SHRFSFCQYP FVISIAAKKI IIQRDSEQQM ISIARQSLVD KVSRRQRPDM NMLFLNMKVR RTHLVSDSLD ELTRKRADLK KKLKVTFVGE AGLDMGGLTK EWFLLLIRQI FHPDYGMFTY HKDSHCHWFS SFKCDNYSEF RLVGILMGLA VYNSITLDIR FPPCCYKKLL SPPVVPSDQS TPVGICSVTI DDLCQVMPEL AHGLKELLSY EGNVEEDFYS TFQVFQEEFG VIKSYNLKPG GDKIPVTNQN RREYVQLYTD FLLNKSIYKQ FAAFYCGFHS VCASNALMLL RPEEVEILVC GSPELDMHAL QRSTQYDGYA KTDLTIRYFW DVVLGFPLEL QKKLLHFTTG SDRVPVGGMA DLNFKISKNE TSTNWLPVAH TCFNQLCLPP YKSKKDLKQK LIIGISNSEG FGLE
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.
  • 基因功能参考文献：
    1. studies describe an unreported innate immune pathway and suggest that mutation or antagonism of the E3 ligase HECTD2 results in reduced severity of lung inflammation by selectively modulating the abundance of the anti-inflammatory protein PIAS1 PMID: 26157031
    2. Hectd2 is identified as a quantitative trait gene for prion disease incubation time in mice. PMID: 19214206
  • 数据库链接：

    KEGG: mmu:226098

    STRING: 10090.ENSMUSP00000128387

    UniGene: Mm.61107