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  4. Recombinant Mouse Phosphorylated CTD-interacting factor 1 (Pcif1)

Recombinant Mouse Phosphorylated CTD-interacting factor 1 (Pcif1)

  • 中文名称：
    小鼠Pcif1重组蛋白
  • 货号：
    CSB-YP017612MO
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    小鼠Pcif1重组蛋白
  • 货号：
    CSB-EP017612MO
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    小鼠Pcif1重组蛋白
  • 货号：
    CSB-EP017612MO-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    小鼠Pcif1重组蛋白
  • 货号：
    CSB-BP017612MO
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    小鼠Pcif1重组蛋白
  • 货号：
    CSB-MP017612MO
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    Pcif1
  • Uniprot No.：
  • 别名：
    Pcif1; mRNA; 2'-O-methyladenosine-N(6)-)-methyltransferase; EC 2.1.1.62; Cap-specific adenosine methyltransferase; CAPAM; Phosphorylated CTD-interacting factor 1
  • 种属：
    Mus musculus (Mouse)
  • 蛋白长度：
    Full length protein
  • 表达区域：
    1-706
  • 氨基酸序列
    MANENHGSPR EGASLLSHSP GTSSQSQPCS PKPVRLVQDL PEELVHAGWE KCWSRRESRP YYFNRFTNQS LWEMPVLGQH DVLSDPLGLN ATPLPQDSSL VETPPVENKS RKRQLSEEQP SGNGVKKPKI EIPVTPTSQS VPSSPSIPGT PTLKIWGSST EDKQAALLRP TEVYWDLDIQ TNAVIKHRGP SEVLPPHPDV ELLRSQLILK LRQHYRELCQ QREGIEPPRE SFNRWMLERK VVDKGCDPLL PSNCEPVVSP SMFREIMNDI PIRLSRIKFR EEAKRLLFKY AEAARRLIES RSASPDSRKV VKWNVEDTFS WLRKEHSASK EDYMDRLEHL RRQCGPHVSA AAKDSVEGIC SKIYHISLEY VKRIREKHLA VLKENNIPEE VEASELEPRL VYCYPVRLAV SAPPMPSVEM HVENSVVCIR YKGEMVKVSR SYFSKLWLLY RYSCVDDSAF ERFLPRVWCL LRRYQMMFGV GLYEGTGLQG SLPVHVFETL HRLFGVSFEC FASPLNCYFR QYCSAFPDTD GYFGSRGPCL DFTPLSGSFE ANPPFCEELM DAMVSHFEKL LESSAEPLSF IVFIPEWREP PTPALTRMEQ SRFKRHQLVL PAFEHEYRSG SQHICKKEEM HYKAVHNTAV LFLQNGPGFA KWGPTPERLQ ELTAAYKQSG RSHGSSSSSS SSSSSSEAKD RDSGREQGPS REPHPT
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Cap-specific adenosine methyltransferase that catalyzes formation of N(6),2'-O-dimethyladenosine cap (m6A(m)) by methylating the adenosine at the second transcribed position of capped mRNAs. Recruited to the early elongation complex of RNA polymerase II (RNAPII) via interaction with POLR2A and mediates formation of m6A(m) co-transcriptionally.
  • 基因功能参考文献：
    1. in adult mouse beta cells, Pcif1 limits Pdx1 protein accumulation and thus the expression of insulin and other gene targets important in the maintenance of beta cell mass and function. PMID: 20811152
  • 亚细胞定位：
    Nucleus.
  • 数据库链接：

    KEGG: mmu:228866

    STRING: 10090.ENSMUSP00000039555

    UniGene: Mm.241134