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  4. Recombinant Mouse Nucleoside diphosphate kinase homolog 5 (Nme5)

Recombinant Mouse Nucleoside diphosphate kinase homolog 5 (Nme5)

  • 中文名称：
    小鼠Nme5重组蛋白
  • 货号：
    CSB-YP859984MO
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    小鼠Nme5重组蛋白
  • 货号：
    CSB-EP859984MO
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    小鼠Nme5重组蛋白
  • 货号：
    CSB-EP859984MO-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    小鼠Nme5重组蛋白
  • 货号：
    CSB-BP859984MO
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    小鼠Nme5重组蛋白
  • 货号：
    CSB-MP859984MO
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    Nme5
  • Uniprot No.：
  • 别名：
    Nme5; Nucleoside diphosphate kinase homolog 5; NDK-H 5; NDP kinase homolog 5; nm23-M5
  • 种属：
    Mus musculus (Mouse)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-211
  • 氨基酸序列
    MEVSMPLPQI YVEKTLALIK PDVVDKEEEI QDIILGSGFT IIQRRKLHLS PEHCSNFYVE QYGKMFFPNL TAYMSSGPLV AMILARHKAI SYWKELMGPS NSLVAKETHP DSLRAIYGTD ELRNALHGSN DFAASEREIR FMFPAVIIEP IPIGQAAKDY INLYVAPTLL QGLTELCKEK PPDPYLWLAD WLMKNNPNKP KLCHFPVTEE P
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Does not seem to have NDK kinase activity. Confers protection from cell death by Bax and alters the cellular levels of several antioxidant enzymes including Gpx5. May play a role in spermiogenesis by increasing the ability of late-stage spermatids to eliminate reactive oxygen species.
  • 基因功能参考文献：
    1. Situs inversus, hydrocephalus, suppurative rhinosinusitis,and sperm flagellar defects in Nme5 null mice are indicative of defective ciliogenesis PMID: 21746835
    2. nm23-M5 gene plays an important role in late spermiogenesis by elevating the ability of late-stage spermatids to eliminate reactive oxygen species PMID: 12788088
    3. results reveal that expression of Nm23-M5 plays a critical role in spermiogenesis by increasing the cellular levels of GPX-5 to eliminate reactive oxygen species PMID: 19303412
    4. Nme5 is most abundantly expressed in tissues rich in highly ciliated cells, such as olfactory sensory neurons, and is predicted to be important to cilia. PMID: 17971504
  • 亚细胞定位：
    Cell projection, cilium.
  • 蛋白家族：
    NDK family
  • 组织特异性：
    Expressed in the trachea, ependymal cells and oviduct (at protein level). Expressed predominantly in germ cells of the testis. Not expressed in testicular somatic cells.
  • 数据库链接：

    KEGG: mmu:75533

    STRING: 10090.ENSMUSP00000078269

    UniGene: Mm.275430