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Recombinant Mouse Nuclear pore complex protein Nup85 (Nup85)

  • 中文名称:
    小鼠Nup85重组蛋白
  • 货号:
    CSB-YP823180MO
  • 规格:
  • 来源:
    Yeast
  • 其他:
  • 中文名称:
    小鼠Nup85重组蛋白
  • 货号:
    CSB-EP823180MO
  • 规格:
  • 来源:
    E.coli
  • 其他:
  • 中文名称:
    小鼠Nup85重组蛋白
  • 货号:
    CSB-EP823180MO-B
  • 规格:
  • 来源:
    E.coli
  • 共轭:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名称:
    小鼠Nup85重组蛋白
  • 货号:
    CSB-BP823180MO
  • 规格:
  • 来源:
    Baculovirus
  • 其他:
  • 中文名称:
    小鼠Nup85重组蛋白
  • 货号:
    CSB-MP823180MO
  • 规格:
  • 来源:
    Mammalian cell
  • 其他:

产品详情

  • 纯度:
    >85% (SDS-PAGE)
  • 基因名:
    Nup85
  • Uniprot No.:
  • 别名:
    Nup85; Pcnt1; Nuclear pore complex protein Nup85; 85 kDa nucleoporin; FROUNT; Nucleoporin Nup85; Pericentrin-1
  • 种属:
    Mus musculus (Mouse)
  • 蛋白长度:
    full length protein
  • 表达区域:
    1-656
  • 氨基酸序列
    MEELDCEPAV TWIPGVNSKK KQMCFDWGPG EMLLCETSFN QTGKSEKVPS CPFIYIIRKD VDVYSQILRK LFNESHGIFV GLQKIEEELS GKSRKAQLVR VSKNYRSVIR ACMEEMHQVA IAAKDPASGR QFSSQVSILS AMELIWNLCE ILFIEVAPAG PLLLHLLDWV RLHVCEVDSL SADVLGGDNP SKHENFWDLV TVLVLQGRLD EARQMLAKEA DANPSCAGMC RVLGDLMRTM PILSPGNTQT LTELELKWQH WREECERHLQ DNTFAANPRL ESLCKIMLGD EAALLEQKEL LSNWYHFLVT RLLYSNPTVK PIDLHFYAQS SLDMFLGGES SPEPLDNILM AAFEFDIHQV IKECSIALSN WWFVAHLTDL LDHCRLLQSH NLYFGSNMRE FLLLEYASGL FAHHSLWQLG VDYFDYCPEL GRVSLELHIE RIPLNTEQKA LKVLRICEQR QMTEQVKSIC KILAMKAVRN NRLGSALSWS IRAKDAAFAT LVSDRFLRDY CERGCFSDLD LIDNLGSAMM LSDRLTFLGK YREFHRLYGE KRFGDAASLL LSLMTSQIAP RSFWMTLLTD ALPLLEQKQV IFSAEQTYEL MRCLEDLASG RPECGEPDAQ RLQDDDIETT KVEMLRLALA RNLARAIIRE GSLEGS
  • 蛋白标签:
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

产品评价

靶点详情

  • 功能:
    Essential component of the nuclear pore complex (NPC) that seems to be required for NPC assembly and maintenance. As part of the NPC Nup107-160 subcomplex plays a role in RNA export and in tethering NUP96/Nup98 and NUP153 to the nucleus. The Nup107-160 complex seems to be required for spindle assembly during mitosis. NUP85 is required for membrane clustering of CCL2-activated CCR2. Seems to be involved in CCR2-mediated chemotaxis of monocytes and may link activated CCR2 to the phosphatidyl-inositol 3-kinase-Rac-lammellipodium protrusion cascade. Involved in nephrogenesis.
  • 基因功能参考文献:
    1. FROUNT links activated CCR2 to the PI(3)K-Rac-lamellipodium protrusion cascade in monocyte chemotaxis PMID: 15995708
  • 亚细胞定位:
    Nucleus, nuclear pore complex. Chromosome, centromere, kinetochore. Cytoplasm, cytoskeleton, spindle. Cytoplasm. Nucleus membrane.
  • 蛋白家族:
    Nucleoporin Nup85 family
  • 数据库链接:

    KEGG: mmu:445007

    STRING: 10090.ENSMUSP00000021085

    UniGene: Mm.4379