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  4. Recombinant Mouse Nitric oxide-associated protein 1 (Noa1)

Recombinant Mouse Nitric oxide-associated protein 1 (Noa1)

  • 中文名称：
    小鼠Noa1重组蛋白
  • 货号：
    CSB-YP884927MO
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    小鼠Noa1重组蛋白
  • 货号：
    CSB-EP884927MO
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    小鼠Noa1重组蛋白
  • 货号：
    CSB-EP884927MO-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    小鼠Noa1重组蛋白
  • 货号：
    CSB-BP884927MO
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    小鼠Noa1重组蛋白
  • 货号：
    CSB-MP884927MO
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    Noa1
  • Uniprot No.：
  • 别名：
    Noa1; MNCb-4931Nitric oxide-associated protein 1
  • 种属：
    Mus musculus (Mouse)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-693
  • 氨基酸序列
    MLPARLACGL LCGLRRGPAP AAACYGPARW LLEGKCEVPI RQRASSLGRR VPPSSTATED YAEGPDTEER FLFPEYVPER TPEEQVRELQ ELRELQQLQQ EKERERLQQR EERLQQKLRA GFRTLPVPEF PDASVPPSGI YCSGCGAELH CQHPGLPGYL PEEKFRDAAQ AEGGPARTVC QRCWLLVHHG RALRLQVSRD QYLELVSAAL RRPGPALVLY MVNLLDLPDA LLPDLPKLVG PKQLIVLGNK VDLLPQDAPG YLKRLRKRLW DDCIRAGLVV APGHQGPQYP AGDEPLEEIK NQNPSSRSRT VVKDVRLISA KTGYGVEEMI SALQRSWRYR GDVYLVGTTN AGKSTLFNTL LESDYCTAKG SEAIDRATIS PWPGTTLNLL KFPICNPTPY RMFKRQRRLQ EDATKAEEDL SEEEQSQLNQ LKKHGYIVGR VGRTFSYSRE QDEVPFEFDA DSLAFDMGSE PVVSVCKSTK QIELTPEDVK DAHWFYDTPG ITKESCILNL LTEKEINTVL PTHSIIPRTF VLKPGMVLFL GGIARIDFLQ GNQSAWFTVV ASNFLPVHIT SLDKADALYE KHAGHELLLV PMGGKERMAQ FPPLVAEDIT LKGGGKFEAV ADIKFSSAGW VAVTPYSEGT LHLRGHTPEG TALTVHPPVL PYIVNVKGQR MKKSVAYKTK KPPSLVHNLK KHR
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Involved in regulation of mitochondrial protein translation and respiration. Plays a role in mitochondria-mediated cell death. May act as a scaffolding protein or stabilizer of respiratory chain supercomplexes. Binds GTP.
  • 基因功能参考文献：
    1. Our results uncovered an unexpected, mandatory detour of NOA1 through the nucleolus before uptake into mitochondria. PMID: 25072814
    2. NOA1 binds specifically to oligonucleotides that fold into guanine tetrads (G-quadruplexes). PMID: 23933583
    3. data show that NOA1 is required for mitochondrial protein synthesis, likely due to its yet unidentified role in mitoribosomal biogenesis; NOA1 is required for such basal mitochondrial functions as adenosine triphosphate (ATP) synthesis and apoptosis PMID: 21118999
  • 亚细胞定位：
    Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
  • 蛋白家族：
    TRAFAC class YlqF/YawG GTPase family, NOA1 subfamily
  • 组织特异性：
    Expressed in tissues associated with high mitochondria content including testes, heart, liver, brain and thymus. Also expressed in various bone cell lines.
  • 数据库链接：

    KEGG: mmu:56412

    STRING: 10090.ENSMUSP00000045948

    UniGene: Mm.129136