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  4. Recombinant Mouse Neuronal membrane glycoprotein M6-b (Gpm6b), partial

Recombinant Mouse Neuronal membrane glycoprotein M6-b (Gpm6b), partial

  • 中文名称：
    小鼠Gpm6b重组蛋白
  • 货号：
    CSB-YP009723MO1
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    小鼠Gpm6b重组蛋白
  • 货号：
    CSB-EP009723MO1
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    小鼠Gpm6b重组蛋白
  • 货号：
    CSB-EP009723MO1-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    小鼠Gpm6b重组蛋白
  • 货号：
    CSB-BP009723MO1
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    小鼠Gpm6b重组蛋白
  • 货号：
    CSB-MP009723MO1
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    Gpm6b
  • Uniprot No.：
  • 别名：
    Gpm6b; M6b; Neuronal membrane glycoprotein M6-b; M6b
  • 种属：
    Mus musculus (Mouse)
  • 蛋白长度：
    Partial
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    May be involved in neural development. Involved in regulation of osteoblast function and bone formation. Involved in matrix vesicle release by osteoblasts; this function seems to involve maintenance of the actin cytoskeleton. May be involved in cellular trafficking of SERT and thereby in regulation of serotonin uptake.
  • 基因功能参考文献：
    1. Study identified glycoprotein M6B as a Schwann cell microvilli component of peripheral nodes of Ranvier. Study detected Na(+) channel clusters at heminodes without any associated M6B, indicating that it is not required for initial channel clustering; showed that absence of M6B results in progressive appearance of nodal protrusions of the nodal axolemma, that are often accompanied by the presence of enlarged mitochondria. PMID: 29282769
    2. The results of this study proposed that M6b proteins are required for proper extension and guidance of callosal axons that follow one of the most complex trajectories in the mammalian nervous system. PMID: 24917275
    3. M6B is not efficiently sorted into mature myelin, in which it is 200-fold less abundant than proteolipid protein (PLP). PMID: 23322581
  • 亚细胞定位：
    Membrane; Multi-pass membrane protein. Cell membrane. Note=Colocalizes with SERT at the plasma membrane.
  • 蛋白家族：
    Myelin proteolipid protein family
  • 组织特异性：
    Widely expressed. In the brain, expressed in neurons and oligodendrocytes.
  • 数据库链接：

    KEGG: mmu:14758

    UniGene: Mm.222320