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  4. Recombinant Mouse Metastasis-associated protein MTA3 (Mta3)

Recombinant Mouse Metastasis-associated protein MTA3 (Mta3)

  • 中文名称：
    小鼠Mta3重组蛋白
  • 货号：
    CSB-YP852877MO
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    小鼠Mta3重组蛋白
  • 货号：
    CSB-EP852877MO
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    小鼠Mta3重组蛋白
  • 货号：
    CSB-EP852877MO-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    小鼠Mta3重组蛋白
  • 货号：
    CSB-BP852877MO
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    小鼠Mta3重组蛋白
  • 货号：
    CSB-MP852877MO
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    Mta3
  • Uniprot No.：
  • 别名：
    Mta3; Metastasis-associated protein MTA3
  • 种属：
    Mus musculus (Mouse)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-591
  • 氨基酸序列
    MAANMYRVGD YVYFENSSSN PYLIRRIEEL NKTASGNVEA KVVCFYRRRD ISNTLIMLAD KHAKETEEES ETPVEADLTE KQKHQLKHRE LFLSRQYESL PATHIRGKCS VALLNETESV LSYLDKEDTF FYSLVYDPSV KTLLADKGEI RVGPKYQADI PDMLPEDSDE REQSKLEVKV WDPNSPLTDR QIDQFLVVAR AVGTFARALD CSSSVRQPSL HMSAAAASRD ITLFHAMDTL YRHGYDLSSA ISVLVPLGGP VLCRDEMEEW SASEACLFEE ALEKYGKDFN DIRQDFLPWK SLTSIIEYYY MWKTTDRYVQ QKRLKAAEAE SKLKQVYIPT YKPNPNQISS SNGKAGTVNG AVGTQFQPQS ALLGRACESC YATQSHQWYS WGPPNMQCRL CATCWLYWKK YGGLKMPTQS DEEKSPSPTA EDPRARSHMS RQALQGMPVR NTGSPKSAVK TRQAFFLRTT YFTKIARQVC KSTLRLRQAA RRPFVAINYA AIRAEYADRH AELSGSPLKS RSTRKPLSCI IGYLEIHPAK KPNVIRSPPS LQTPATKRML AAPNHTSLSI LGKRNYSHHN GLDGPERWLS R
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Plays a role in maintenance of the normal epithelial architecture through the repression of SNAI1 transcription in a histone deacetylase-dependent manner, and thus the regulation of E-cadherin levels. Contributes to transcriptional repression by BCL6.
  • 基因功能参考文献：
    1. data are the first to disclose the presence and functional role of MTA3 in the testis, where its expression is regulated by developmental, metabolic, and hormonal cues and is closely associated with steroidogenic dysfunction. The PMID: 27673553
    2. Bcl6 middle domain repressor function is required for T follicular helper cell differentiation and utilizes the corepressor MTA3. PMID: 26460037
    3. Metastasis-associated protein 3 (MTA3) regulates G2/M progression in proliferating mouse granulosa cells. PMID: 22075476
  • 亚细胞定位：
    Nucleus. Cytoplasm.
  • 组织特异性：
    Expressed in heart, brain, spleen, lung, liver and kidney.
  • 数据库链接：

    KEGG: mmu:116871

    STRING: 10090.ENSMUSP00000068931

    UniGene: Mm.277668