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  4. Recombinant Mouse IQ calmodulin-binding motif-containing protein 1 (Iqcb1)

Recombinant Mouse IQ calmodulin-binding motif-containing protein 1 (Iqcb1)

  • 中文名称：
    小鼠Iqcb1重组蛋白
  • 货号：
    CSB-YP805314MO
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    小鼠Iqcb1重组蛋白
  • 货号：
    CSB-EP805314MO
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    小鼠Iqcb1重组蛋白
  • 货号：
    CSB-EP805314MO-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    小鼠Iqcb1重组蛋白
  • 货号：
    CSB-BP805314MO
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    小鼠Iqcb1重组蛋白
  • 货号：
    CSB-MP805314MO
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    Iqcb1
  • Uniprot No.：
  • 别名：
    Iqcb1; Kiaa0036; IQ calmodulin-binding motif-containing protein 1
  • 种属：
    Mus musculus (Mouse)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-598
  • 氨基酸序列
    MKPAGTDPRI LSLAAEVAKS PEQNVPVILL KLKEIINNTP LGSSELKKVK QDIYCYDLIQ YCLLVLSQDS SRIQGGWSTI SQLTQILSHC CVGLEPGEDG EEFYKELLPS AAENFLILGR RLQTCFINAT KGEEQDKLLH FFQIVTDSLF WLLGGHVQLI QNVLQSDHFL HLLQTDNVQI GASVMTLLQN ILQINSGNLL KIEGKALHSI LDEILFKLLS TPSPVIRSTA TKLLLVLAES HQEILILLRL SACYKGLRSL LNKQETLTEF SRELRQLVDL LTPKIHQEVE EQKLHKAACL IQAYWKGFQT RKRLKKLPSA VIALQRSFRS KRTKMMLELN RQKEEEDLRL KLQLQRQRAM RLSRESRLNM LEIIHPGQVE KYNREMEEKS ALTIQKHWRG YRERKNFRQQ RPSLTEYKAA VTLQRAVLKF LAKCRKKKKL FASWHGLQEL TDARRVELKQ QVDDYVKRHP CSQMSEAASR ELHAQAQERL QHYFMGRAIE ERAQQHREAL MAQISTNIEQ LMKAPSLKEA EGKEPEQFLS RSRPVAAKAK QAHLTTLKHI QAPWWKKLGE EPGDEVDVPK DELSIDLGML FIGGTKPP
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Involved in ciliogenesis. The function in an early step in cilia formation depends on its association with CEP290/NPHP6. Involved in regulation of the BBSome complex integrity, specifically for presence of BBS2 and BBS5 in the complex, and in ciliary targeting of selected BBSome cargos. May play a role in controlling entry of the BBSome complex to cilia possibly implicating CEP290/NPHP6.
  • 基因功能参考文献：
    1. Nphp5(-/-) photoreceptor degeneration was complete at 1 mo of age but was delayed significantly in Nphp5(-/-);Nrl(-/-) (cone only) retina PMID: 27328943
  • 亚细胞定位：
    Cytoplasm, cytoskeleton, microtubule organizing center, centrosome.
  • 组织特异性：
    Localized to the outer segment and connecting cilia of photoreceptor cells.
  • 数据库链接：

    KEGG: mmu:320299

    STRING: 10090.ENSMUSP00000023535

    UniGene: Mm.222934