Your Good Partner in Biology Research

  1. 首页
  2. 蛋白
  3. 重组蛋白
  4. Recombinant Mouse Homeobox protein Hox-C13 (Hoxc13)

Recombinant Mouse Homeobox protein Hox-C13 (Hoxc13)

  • 中文名称：
    小鼠Hoxc13重组蛋白
  • 货号：
    CSB-YP010674MO
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    小鼠Hoxc13重组蛋白
  • 货号：
    CSB-EP010674MO
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    小鼠Hoxc13重组蛋白
  • 货号：
    CSB-EP010674MO-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    小鼠Hoxc13重组蛋白
  • 货号：
    CSB-BP010674MO
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    小鼠Hoxc13重组蛋白
  • 货号：
    CSB-MP010674MO
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    Hoxc13
  • Uniprot No.：
  • 别名：
    Hoxc13; Hoxc-13; Homeobox protein Hox-C13
  • 种属：
    Mus musculus (Mouse)
  • 蛋白长度：
    Full length protein
  • 表达区域：
    1-328
  • 氨基酸序列
    MTTSLLLHPR WPESLMYVYE DSAAESGSGG GGGGGGAGGA GGGCSGASPG KAPSMDGLGG SCPASHCRDL LPHPVLARPP APLGAPQGAV YTDIPAPEAA RQCAPPPAPP TSSSATLGYG YPFGGSYYGC RLSHNVNLQQ KPCAYHPGDK YPEPSGALPG DDLSSRAKEF AFYPSFASSY QAMPGYLDVS VVPGISGHPE PRHDALIPVE GYQHWALSNG WDSQVYCSKE QSQSAHLWKS PFPDVVPLQP EVSSYRRGRK KRVPYTKVQL KELEKEYAAS KFITKEKRRR ISATTNLSER QVTIWFQNRR VKEKKVVSKS KAPHLHST
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Transcription factor which plays a role in hair follicle differentiation. Regulates FOXQ1 expression and that of other hair-specific genes.
  • 基因功能参考文献：
    1. Here we demonstrate that the transcription factors SPI1 (PU.1) and HOXC13 synergistically regulate Zfp521 expression, and identify the regions of the Zfp521 promoter required for this transcriptional activity. We also show that SPI1 and HOXC13 activate Zfp521 in a dose-dependent manner. PMID: 27506447
    2. data strongly suggest that Hoxc13 is a novel and crucial regulator of the hair cycle. PMID: 26553656
    3. a potential regulatory relationship between the sterol O-acetyltransferase 1 gene and Hoxc13 gene PMID: 26321246
    4. Krtap16 is a hair keratin-associated protein gene complex regulated by Hoxc13 PMID: 15385554
    5. We provide evidence for specific interaction of Hoxc13 with at least one cognate binding site found in the Crisp1 promoter region. PMID: 16382673

    显示更多

    收起更多

  • 亚细胞定位：
    Nucleus.
  • 蛋白家族：
    Abd-B homeobox family
  • 组织特异性：
    Expressed in differentiating keratinocytes. In the hair follicle lower matrix, expressed in all 3 hair shaft-forming compartments, i.e. cuticle, cortex and medulla. Expression stops sharply at the boundary with the germinal matrix compartment.
  • 数据库链接：

    KEGG: mmu:15422

    STRING: 10090.ENSMUSP00000001700

    UniGene: Mm.207062