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  4. Recombinant Mouse Heat shock protein beta-7 (Hspb7)

Recombinant Mouse Heat shock protein beta-7 (Hspb7)

  • 中文名称：
    小鼠Hspb7重组蛋白
  • 货号：
    CSB-YP010838MO
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    小鼠Hspb7重组蛋白
  • 货号：
    CSB-EP010838MO
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    小鼠Hspb7重组蛋白
  • 货号：
    CSB-EP010838MO-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    小鼠Hspb7重组蛋白
  • 货号：
    CSB-BP010838MO
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    小鼠Hspb7重组蛋白
  • 货号：
    CSB-MP010838MO
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    Hspb7
  • Uniprot No.：
  • 别名：
    Hspb7; Cvhsp; Hsp25-2Heat shock protein beta-7; HspB7; Cardiovascular heat shock protein; cvHsp; Heat shock protein 25 kDa 2; Protein p19/6.8
  • 种属：
    Mus musculus (Mouse)
  • 蛋白长度：
    Full length protein
  • 表达区域：
    1-169
  • 氨基酸序列
    MSHRTSSAFR AERSFRSSSS SSSSSSSSAS RALPAQDPPM EKALSMFSDD FGSFMLPHSE PLAFPARPGG QGNIKTLGDA YEFTVDMRDF SPEDIIVTTF NNHIEVRAEK LAADGTVMNT FAHKCQLPED VDPTSVTSAL REDGSLTIRA RRHPHTEHVQ QTFRTEIKI
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 基因功能参考文献：
    1. The s found that deleting HSPB7 resulted in uncontrolled elongation of actin filaments and the formation of atypical actin filament bundles in cardiomyocytes. PMID: 29078393
    2. our findings characterize HSPB7 as an intercalated disc protein and suggest it has an essential role in maintaining intercalated disc integrity and conduction function in the adult heart. PMID: 28827800
    3. these data indicate that MEF2 and AP-1 confer antagonistic regulation of Hspb7 gene expression in skeletal muscle, with implications for autophagy and muscle atrophy. PMID: 27632998
    4. this paper shows that skeletal-muscle-specific ablation of the HspB7 causes postnatal death owing to a respiration defect, with progressive myopathy phenotypes in the diaphragm PMID: 26929074
    5. HSPB7 is a potential early biomarker after MI and serves as an independent risk factor of ACS in patients with acute chest pain. PMID: 22785082
    6. These results imply that HspB2 and HspB7 might be up-regulated by ethanol during the short-term differentiation of neural stem cells. PMID: 20871982

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  • 亚细胞定位：
    Cytoplasm. Nucleus. Nucleus, Cajal body.
  • 蛋白家族：
    Small heat shock protein (HSP20) family
  • 组织特异性：
    Found in both cardiac and slow skeletal (soleus) muscle.
  • 数据库链接：

    KEGG: mmu:29818

    STRING: 10090.ENSMUSP00000099544

    UniGene: Mm.46181