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  4. Recombinant Mouse Flt3-interacting zinc finger protein 1 (Fiz1)

Recombinant Mouse Flt3-interacting zinc finger protein 1 (Fiz1)

  • 中文名称：
    小鼠Fiz1重组蛋白
  • 货号：
    CSB-YP893401MO
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    小鼠Fiz1重组蛋白
  • 货号：
    CSB-EP893401MO
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    小鼠Fiz1重组蛋白
  • 货号：
    CSB-EP893401MO-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    小鼠Fiz1重组蛋白
  • 货号：
    CSB-BP893401MO
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    小鼠Fiz1重组蛋白
  • 货号：
    CSB-MP893401MO
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    Fiz1
  • Uniprot No.：
  • 别名：
    Fiz1Flt3-interacting zinc finger protein 1
  • 种属：
    Mus musculus (Mouse)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-500
  • 氨基酸序列
    MEDSSLPVVP APIAAPGPAP SATAPRVPFH CSECGKSFRY RSDLRRHFAR HTALKPHACP RCGKGFKHSF NLANHLRSHT GERPYRCSAC PKGFRDSTGL LHHQVVHTGE KPYCCLVCEL RFSSRSSLGR HLKRQHRGTL PSPLQPSPGL PPLSSPCSVC CNVGPCSVCG GGGSSGGEGL EGAGATSWGL AEAAAAAAAS LPPFACGACA RRFDHGRELA AHWAAHTDVK PFKCPRCERD FNAPALLERH KLTHDLQGSN APPTQVWASG GGPEVAGEGD ASEVGAAPQT WDAGLLLSPT GAGVPKLEAL LPGDEGSGND QAPAAAAEAS SEDTLYQCDC GTFFASAPAL ASHLEAHSGP ATYGCGHCGA LYAALAALEE HRRASHGEGS GEAAPDGEGN QAAGGPGPGS SSRSKKIFGC SECEKLFRSP RDLERHVLVH TGEKPFPCLE CGKFFRHECY LKRHRLLHGT ERPFPCHICG KGFITLSNLS RHLKLHRGMD
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    May be a transcriptional repressor of NRL function in photoreceptors. Does not repress CRX-mediated transactivation.
  • 基因功能参考文献：
    1. FLT3 and CD43 signaling pathways involve STAT5A via Fiz1 and Hipk2 in B lymphoblastic lymphomas. PMID: 20360400
    2. Addition of potent FLT3 inhibitors such as SU11248 to acute myeloid leukemia chemotherapy regimens could result in improved treatment results. PMID: 15304385
    3. Fiz1 is part of the regulatory protein complex on active photoreceptor-specific gene promoters in vivo. PMID: 18854042
  • 亚细胞定位：
    Cytoplasm. Nucleus.
  • 组织特异性：
    Widely expressed. In the retina, highest expression in the ganglion cell layer.
  • 数据库链接：

    KEGG: mmu:23877

    STRING: 10090.ENSMUSP00000076603

    UniGene: Mm.38911