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  4. Recombinant Mouse Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3-phosphoinositide (Dapp1)

Recombinant Mouse Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3-phosphoinositide (Dapp1)

  • 中文名称：
    Recombinant Mouse Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3-phosphoinositide(Dapp1),Yeast
  • 货号：
    CSB-YP874111MO
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    Recombinant Mouse Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3-phosphoinositide(Dapp1),Yeast
  • 货号：
    CSB-EP874111MO
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    Recombinant Mouse Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3-phosphoinositide(Dapp1),Yeast
  • 货号：
    CSB-EP874111MO-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    Recombinant Mouse Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3-phosphoinositide(Dapp1),Yeast
  • 货号：
    CSB-BP874111MO
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    Recombinant Mouse Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3-phosphoinositide(Dapp1),Yeast
  • 货号：
    CSB-MP874111MO
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
  • Uniprot No.：
  • 别名：
    Dapp1; Bam32Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3-phosphoinositide; mDAPP1; B lymphocyte adapter protein Bam32; B-cell adapter molecule of 32 kDa
  • 种属：
    Mus musculus (Mouse)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-280
  • 氨基酸序列
    MGRAELLGGN MSTQDPSELW GRADGGTDLL QDLGWYHGNL TRHAAEALLL SNGRDGSYLL RDSNEQTGLY SLSVRAKDSV KHFHVEYTGY SFKFGFNEYS SLKDFVKHFA NQPLIGSETG TLMVLKHPYP REVEEPCIYE SVRVHTAMQT GRTENDLVPT APSLGTKEGY LTKQGGLVKT WKTRWFTLQR NELKYFKDQM SPEPIRILDL TECSAVQFDY SQERVNCFCL VFPFRTFYLC AKTGVEADEW IKILRWKLSK IRKQLDQGED TVRSRSFIFK
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    May act as a B-cell-associated adapter that regulates B-cell antigen receptor (BCR)-signaling downstream of PI3K.
  • 基因功能参考文献：
    1. These data show that Bam32 is important for optimal anti-trypanosome IgG antibody response and suppression of disease-promoting proinflammatory cytokines. PMID: 25875604
    2. our results identify Bam32 as a novel regulator of mast cell activation PMID: 20956018
    3. The interaction of Bam32 with Lyn leads to Bam32 phosphorylation, which might play an important role in activating downstream signaling molecules. PMID: 15989784
    4. Data show that Erk activation was diminished in LAT knock-in Bam32 knockout CD4(+) T cells. PMID: 19667175
    5. Bam32 is not required for germinal center (GC) initiation, but rather functions in a late checkpoint of GC progression associated with T cell recruitment and GC B cell survival. PMID: 19949096

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  • 亚细胞定位：
    Cytoplasm. Membrane; Peripheral membrane protein.
  • 数据库链接：

    KEGG: mmu:26377

    STRING: 10090.ENSMUSP00000029806

    UniGene: Mm.254835