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  4. Recombinant Mouse Cell cycle exit and neuronal differentiation protein 1 (Cend1), partial

Recombinant Mouse Cell cycle exit and neuronal differentiation protein 1 (Cend1), partial

  • 中文名称：
    Recombinant Mouse Cell cycle exit and neuronal differentiation protein 1(Cend1),partial,Yeast
  • 货号：
    CSB-YP881332MO
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    Recombinant Mouse Cell cycle exit and neuronal differentiation protein 1(Cend1),partial,Yeast
  • 货号：
    CSB-EP881332MO
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    Recombinant Mouse Cell cycle exit and neuronal differentiation protein 1(Cend1),partial,Yeast
  • 货号：
    CSB-EP881332MO-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    Recombinant Mouse Cell cycle exit and neuronal differentiation protein 1(Cend1),partial,Yeast
  • 货号：
    CSB-BP881332MO
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    Recombinant Mouse Cell cycle exit and neuronal differentiation protein 1(Cend1),partial,Yeast
  • 货号：
    CSB-MP881332MO
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    Cend1
  • Uniprot No.：
  • 别名：
    Cend1; Bm88Cell cycle exit and neuronal differentiation protein 1; BM88 antigen
  • 种属：
    Mus musculus (Mouse)
  • 蛋白长度：
    Partial
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Involved in neuronal differentiation.
  • 基因功能参考文献：
    1. data suggest that common reprogramming mechanisms exist driving the conversion of lineage-distant somatic cell types to neurons and reveal a critical role for CEND1 in NEUROG2-driven astrocytic reprogramming. PMID: 26321141
    2. This study suggested that Cend1 is involved in Ahi1-associated hypothalamic neuronal differentiation in early development, giving us fresh insight into the mechanism behind the delayed development in Joubert syndrome. PMID: 23658157
    3. Our results suggest that Cend1 is required for normal cerebellar development. PMID: 20153830
    4. Transplantation of BM88/Cend1-overexpressing neural progenitor cells exerts beneficial effects on tissue regeneration by enhancing the number of generated neurons and restricting the formation of astroglial scar, in a mouse model of cortical brain injury. PMID: 19911428
    5. BM88 is widely expressed in the embryonic CNS and PNS, in both nestin-positive neuroepithelial cells and post-mitotic betaIII-tubulin positive neurons. PMID: 16949349
    6. Results implicate BM88 in the synchronization of cell cycle exit and differentiation of neuronal precursors in the developing nervous system. PMID: 17971443
    7. BM88/Cend1 participates in cell cycle control and neuronal differentiation mechanisms during neonatal SVZ neurogenesis and becomes crucial for the transition from neuroblasts to mature neurons when reaching high levels PMID: 18499894

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  • 亚细胞定位：
    Membrane; Single-pass type IV membrane protein.
  • 蛋白家族：
    CEND1 family
  • 组织特异性：
    Expressed in the brain, including hypothalamus, brainstem, and hippocampus. Expression is high in 1-month-old mouse brain and then declines in mature mouse brains at the age of 3 and 7 months.
  • 数据库链接：

    KEGG: mmu:57754

    STRING: 10090.ENSMUSP00000081476

    UniGene: Mm.87027