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Recombinant Mouse CLK4-associating serine/arginine rich protein (Clasrp)

  • 货号:
    CSB-YP806528MO
  • 规格:
  • 来源:
    Yeast
  • 其他:
  • 货号:
    CSB-EP806528MO
  • 规格:
  • 来源:
    E.coli
  • 其他:
  • 货号:
    CSB-EP806528MO-B
  • 规格:
  • 来源:
    E.coli
  • 共轭:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 货号:
    CSB-BP806528MO
  • 规格:
  • 来源:
    Baculovirus
  • 其他:
  • 货号:
    CSB-MP806528MO
  • 规格:
  • 来源:
    Mammalian cell
  • 其他:

产品详情

  • 纯度:
    >85% (SDS-PAGE)
  • 基因名:
    Clasrp
  • Uniprot No.:
  • 别名:
    Clasrp; Clasp; Sfrs16; Srsf16; Swap2CLK4-associating serine/arginine rich protein; Clk4-associating SR-related protein; Serine/arginine-rich splicing factor 16; Splicing factor; arginine/serine-rich 16; Suppressor of white-apricot homolog 2
  • 种属:
    Mus musculus (Mouse)
  • 蛋白长度:
    full length protein
  • 表达区域:
    1-668
  • 氨基酸序列
    MWHEARKHER KLRGMMVDYK KRAERRREYY EKIKKDPAQF LQVHGRACKV HLDSAVALAA ESPVNMMPWQ GDTNNMIDRF DVRAHLDHIP DYTPPLLTTI SPEQESDERK CNYERYRGLV QNDFAGISEE QCLYQIYIDE LYGGLQRPSE DEKKKLAEKK ASIGYTYEDS TVAEVEKVAE KPEEEESPAE EESNSDEDEV IPDIDVEVDV DELNQEQVAD LNKQATTYGM ADGDFVRMLR KDKEEAEAIK HAKALEEEKA MYSGRRSRRQ RREFREKRLR GRKISPPSYA RRDSPTYDPY KRSPSESSSE SRSRSRSPSP GREEKITFIT SFGGSDEEAA AAAAAAAASG AAPGKPPAPP QTGGPAPGRN ASTRRRSSSS SASRTSSSRS SSRSSSRSRR GYYRSGRHAR SRSRSWSRSR SRSRRYSRSR SRGRRHSDGG SRDGHRYSRS PARRGGYVPR RRSRSRSRSG DRYKRGARGP RHHSSSHSRS SWSLSPSRSR SVTRSGSRSQ SRSRSRSQSH SQSQSHSPSP PREKLTRPAA SPAVGEKLKK TEPAAGKETG AAKPKLTPQE RLKLRMQKAL NRQFKADKKA AQEKMIQQEH ERQEREDELR AMARKIRMKE RERREKEREE WERQYSRQSR SPSPRYSREY SSSRRRSRSR SRSPHYRH
  • 蛋白标签:
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

产品评价

靶点详情

  • 功能:
    Probably functions as an alternative splicing regulator. May regulate the mRNA splicing of genes such as CLK1. May act by regulating members of the CLK kinase family.
  • 基因功能参考文献:
    1. Loss of Upf2 during fetal liver development causes a change in expression of many genes, including Clasrp/Sfrs16 (Table S1). PMID: 20657840
    2. Clasp is a binding partner of Clk4 and may be involved in the regulation of the activity of Clk kinase family PMID: 12169693
  • 亚细胞定位:
    Nucleus. Note=Located in nuclear dots.; [Isoform 2]: Nucleus, nucleoplasm.
  • 蛋白家族:
    Splicing factor SR family
  • 组织特异性:
    Highly expressed in brain. Expressed at intermediate level in lung and liver. In brain, it is expressed in the hippocampus, cerebellum and olfactory bulb.
  • 数据库链接:

    KEGG: mmu:53609

    STRING: 10090.ENSMUSP00000083205

    UniGene: Mm.20913