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  4. Recombinant Mouse Brain-enriched guanylate kinase-associated protein (Begain)

Recombinant Mouse Brain-enriched guanylate kinase-associated protein (Begain)

  • 中文名称：
    Recombinant Mouse Brain-enriched guanylate kinase-associated protein(Begain),Yeast
  • 货号：
    CSB-YP721209MO
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    Recombinant Mouse Brain-enriched guanylate kinase-associated protein(Begain),Yeast
  • 货号：
    CSB-EP721209MO
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    Recombinant Mouse Brain-enriched guanylate kinase-associated protein(Begain),Yeast
  • 货号：
    CSB-EP721209MO-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    Recombinant Mouse Brain-enriched guanylate kinase-associated protein(Begain),Yeast
  • 货号：
    CSB-BP721209MO
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    Recombinant Mouse Brain-enriched guanylate kinase-associated protein(Begain),Yeast
  • 货号：
    CSB-MP721209MO
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    Begain
  • Uniprot No.：
  • 别名：
    BegainBrain-enriched guanylate kinase-associated protein
  • 种属：
    Mus musculus (Mouse)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-600
  • 氨基酸序列
    MEKLSALQEQ KGELRKRLSY TTHKLEKLET EFDSTRHYLE IELRRAQEEL DKVTEKLRRI QSNYMALQRI NQELEDKLYR MGQHYEEEKR AMSHEIVALN SHLLEAKVTI DKLSEDNELY RKDCNLAAQL LQCSQTYGRV HKVSELPSDF QQRVSLHMEK HGCSLPSALC HPAYADSVPT CVIAKVLEKP DPGSLSSRMS DASARDLGYR DGVEKSGPRP PYKGDIYCSD PALYCPDERE HARRPSVDTP VTDVGFLRAQ NSTDSAAEEE EEAEAAAFPE AYRREAYQGY AASLPTSSSY SSFSATSEEK EHAQAGTLTA SQQAIYLSSR DEFFNRKPSA TYGSGPRFAK AASTLGSPLE AQVAPGFART VSPYPAEPYR YPASPGPQQA LMPPNLWSLR AKPSGNRLAG EDIRGQWRPV SVEDVGAYSY QAGAAAGRAA SPCNYSERYY GGGGGGGAAG GGSPGDKAEG RASPLYATYK ADSFSEGDDL SQGHLAEPCF LRAGGDLSLS PSRSADALAG YAASDGDGDR LRVQLCGAGS SPEPEHGSRE SLEPSSMEAS PEMHPPTRLS PQQAFPRTGG SGLSRKDSLT KAQLYGTLLN
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    May sustain the structure of the postsynaptic density (PSD).
  • 基因功能参考文献：
    1. BEGAIN was highly localized at the synapse of inner lamina II in the spinal dorsal horn and that its expression was up-regulated after peripheral nerve injury in wild-type, but not in GluN2B Y1472F-KI, mice. Mechanical allodynia was significantly attenuated in BEGAIN-deficient mice, but no change was observed in terms of physiological threshold for mechanical stimuli. PMID: 27785460
    2. A Begain transcript variant is preferentially expressed from the paternal allele. PMID: 19641963
  • 亚细胞定位：
    Cytoplasm. Membrane; Peripheral membrane protein.
  • 数据库链接：

    KEGG: mmu:380785

    STRING: 10090.ENSMUSP00000072899

    UniGene: Mm.342085