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Recombinant Mouse Beta-parvin (Parvb)

  • 中文名称：
    小鼠Parvb重组蛋白
  • 货号：
    CSB-YP884150MO
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    小鼠Parvb重组蛋白
  • 货号：
    CSB-EP884150MO
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    小鼠Parvb重组蛋白
  • 货号：
    CSB-EP884150MO-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    小鼠Parvb重组蛋白
  • 货号：
    CSB-BP884150MO
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    小鼠Parvb重组蛋白
  • 货号：
    CSB-MP884150MO
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
  • Uniprot No.：
  • 别名：
    Parvb; Beta-parvin
  • 种属：
    Mus musculus (Mouse)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-365
  • 氨基酸序列
    MSSAPPRSPT PRAPKMKKDE SFLGKLGGTL ARKKKTREVT DLQEEGKSAI NSPMAPALVD IHPEDTQLEE NEERTMIDPT SREDPKFKEL VKVLLDWIND VLAEERIIVK QLEEDLYDGQ VLQKLLEKLA HCKLNVAEVT QSEIGQKQKL QTVLEAVQDL LRPHGWPLRW NVDSIHGKNL VAILHLLVSL AMHFRAPIHL PEHVTVQVVV VRKREGLLHS SHISEELTTT TEIMMGRFER DAFDTLFDHA PDKLNLVKKS LITFVNKHLN KLNLEVTDLE TQFADGVYLV LLLGLLEDYF VPLHNFYLTP DSFDQKVHNV AFAFELMLDG GLKKPKARPE DVVNLDLKST LRVLYTLFTK YKDVE
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Adapter protein that plays a role in integrin signaling via ILK and in activation of the GTPases CDC42 and RAC1 by guanine exchange factors, such as ARHGEF6. Is involved in the reorganization of the actin cytoskeleton and formation of lamellipodia. Plays a role in cell adhesion, cell spreading, establishment or maintenance of cell polarity, and cell migration.
  • 基因功能参考文献：
    1. Data from functional molecular imaging demonstrated that beta-parvin plays a regulatory role in the ILK-mediated Akt (also called protein kinase B) signaling cascades, suggesting that beta-parvin might be a crucial modulator of cell survival. PMID: 20164304
    2. Data show that affixin is a dysferlin binding protein that colocalizes with dysferlin at the sarcolemma of normal skeletal muscle. PMID: 15835269
  • 亚细胞定位：
    Cell junction, focal adhesion. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm, cytoskeleton. Cell projection, lamellipodium. Cytoplasm, myofibril, sarcomere. Cytoplasm, myofibril, sarcomere, Z line.
  • 蛋白家族：
    Parvin family
  • 组织特异性：
    Expressed predominantly in heart and moderately in spleen, lung and skeletal muscle.
  • 数据库链接：

    KEGG: mmu:170736

    STRING: 10090.ENSMUSP00000023072

    UniGene: Mm.323892