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Recombinant Mouse Allergin-1 (Milr1), partial

In Stock
  • 中文名称:
    小鼠Milr1重组蛋白
  • 货号:
    CSB-EP662302MO
  • 规格:
    ¥2328
  • 图片:
    • (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
    • Based on the SEQUEST from database of E.coli host and target protein, the LC-MS/MS Analysis result of CSB-EP662302MO could indicate that this peptide derived from E.coli-expressed Mus musculus (Mouse) Milr1.
    • Based on the SEQUEST from database of E.coli host and target protein, the LC-MS/MS Analysis result of CSB-EP662302MO could indicate that this peptide derived from E.coli-expressed Mus musculus (Mouse) Milr1.
  • 其他:

产品详情

  • 纯度:
    Greater than 85% as determined by SDS-PAGE.
  • 基因名:
    Milr1
  • Uniprot No.:
  • 别名:
    Milr1; Gm885; Mca32; Allergin-1; Allergy inhibitory receptor 1; Mast cell antigen 32; MCA-32; Mast cell Ag-32; Mast cell immunoglobulin-like receptor 1
  • 种属:
    Mus musculus (Mouse)
  • 蛋白长度:
    Extracellular Domain
  • 来源:
    E.coli
  • 分子量:
    20.1 kDa
  • 表达区域:
    34-150aa
  • 氨基酸序列
    ITLQNAAVDCTRVENNELPSPNLNSSMNVVRMGQNVSLSCSTKNTSVDITYSLFWGTKYLESKRRRGGAVDFHLRISNANESGPYKCKVNVSNLMKYSQDFNFTMAKDESCPSCRLS
    Note: The complete sequence including tag sequence, target protein sequence and linker sequence could be provided upon request.
  • 蛋白标签:
    N-terminal 10xHis-tagged and C-terminal Myc-tagged
  • 产品提供形式:
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 缓冲液:
    Tris-based buffer,50% glycerol
  • 储存条件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期:
    3-7 business days
  • 注意事项:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet & COA:
    Please contact us to get it.

产品评价

靶点详情

  • 功能:
    Immunoglobulin-like receptor which plays an inhibitory role in degranulation of mast cells. Negatively regulates IgE-mediated mast cell activation and suppresses the type I immediate hypersensitivity reaction.
  • 基因功能参考文献:
    1. The results suggest that Allergin-1 on skin MCs suppresses TLR2-induced dermatitis. PMID: 27932517
    2. It is a immunoglobulin-like receptor which regulates the activation of mast cell.(review) PMID: 24552759
  • 亚细胞定位:
    Cell membrane; Single-pass type I membrane protein.; [Isoform 2]: Secreted.
  • 组织特异性:
    Expressed in myeloid cells (dendritic cells, macrophages and neutrophils but not in T-cells, B-cells or natural killer cells) and mast cells (at protein level).
  • 数据库链接:

    KEGG: mmu:380732

    UniGene: Mm.343952