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  4. Recombinant Mouse Activator of 90 kDa heat shock protein ATPase homolog 1 (Ahsa1)

Recombinant Mouse Activator of 90 kDa heat shock protein ATPase homolog 1 (Ahsa1)

  • 中文名称：
    Recombinant Mouse Activator of 90 kDa heat shock protein ATPase homolog 1(Ahsa1),Yeast
  • 货号：
    CSB-YP803890MO
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    Recombinant Mouse Activator of 90 kDa heat shock protein ATPase homolog 1(Ahsa1),Yeast
  • 货号：
    CSB-EP803890MO
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    Recombinant Mouse Activator of 90 kDa heat shock protein ATPase homolog 1(Ahsa1),Yeast
  • 货号：
    CSB-EP803890MO-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    Recombinant Mouse Activator of 90 kDa heat shock protein ATPase homolog 1(Ahsa1),Yeast
  • 货号：
    CSB-BP803890MO
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    Recombinant Mouse Activator of 90 kDa heat shock protein ATPase homolog 1(Ahsa1),Yeast
  • 货号：
    CSB-MP803890MO
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    Ahsa1
  • Uniprot No.：
  • 别名：
    Ahsa1; Activator of 90 kDa heat shock protein ATPase homolog 1; AHA1
  • 种属：
    Mus musculus (Mouse)
  • 蛋白长度：
    Full Length of Mature Protein
  • 表达区域：
    2-338
  • 氨基酸序列
    AKWGEGDPR WIVEERADAT NVNNWHWTER DASNWSTEKL KTLFLAVRVE NEEGKCEVTE VNKLDGEASI NNRKGKLIFF YEWTIKLNWT GTSKSGVQYK GHVEIPNLSD ENSVDEVEIS VSLAKDEPDT NLVALMKEDG VKLLREAVGI YISTLKTEFT QGMILPTVNG ESVDPVGQPA LKTETCKAKS APSKSQAKPV GVKIPTCKIT LKETFLTSPE ELYRVFTTQE LVQAFTHAPA ALEADRGGKF HMVDGNVTGE FTDLVPEKHI AMKWRFKSWP EGHFATITLT FIDKNGETEL CMEGRGIPAP EEERTRQGWQ RYYFEGIKQT FGYGARLF
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Acts as a co-chaperone of HSP90AA1. Activates the ATPase activity of HSP90AA1 leading to increase in its chaperone activity. Competes with the inhibitory co-chaperone FNIP1 for binding to HSP90AA1, thereby providing a reciprocal regulatory mechanism for chaperoning of client proteins. Competes with the inhibitory co-chaperone TSC1 for binding to HSP90AA1, thereby providing a reciprocal regulatory mechanism for chaperoning of client proteins.
  • 基因功能参考文献：
    1. Hsp90 phosphorylation on tyrosine313 promotes recruitment of AHA1, which stimulates Hsp90 ATPase activity, furthering the chaperoning process. PMID: 22727666
  • 亚细胞定位：
    Cytoplasm, cytosol. Endoplasmic reticulum.
  • 蛋白家族：
    AHA1 family
  • 数据库链接：

    KEGG: mmu:217737

    STRING: 10090.ENSMUSP00000021425

    UniGene: Mm.22626