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  4. Recombinant Mouse Acidic leucine-rich nuclear phosphoprotein 32 family member E (Anp32e)

Recombinant Mouse Acidic leucine-rich nuclear phosphoprotein 32 family member E (Anp32e)

  • 中文名称：
    Recombinant Mouse Acidic leucine-rich nuclear phosphoprotein 32 family member E(Anp32e),Yeast
  • 货号：
    CSB-YP001826MO
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    Recombinant Mouse Acidic leucine-rich nuclear phosphoprotein 32 family member E(Anp32e),Yeast
  • 货号：
    CSB-EP001826MO
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    Recombinant Mouse Acidic leucine-rich nuclear phosphoprotein 32 family member E(Anp32e),Yeast
  • 货号：
    CSB-EP001826MO-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    Recombinant Mouse Acidic leucine-rich nuclear phosphoprotein 32 family member E(Anp32e),Yeast
  • 货号：
    CSB-BP001826MO
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    Recombinant Mouse Acidic leucine-rich nuclear phosphoprotein 32 family member E(Anp32e),Yeast
  • 货号：
    CSB-MP001826MO
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    Anp32e
  • Uniprot No.：
  • 别名：
    Anp32e; Cpd1; Acidic leucine-rich nuclear phosphoprotein 32 family member E; Cerebellar postnatal development protein 1; LANP-like protein; LANP-L
  • 种属：
    Mus musculus (Mouse)
  • 蛋白长度：
    Full length protein
  • 表达区域：
    1-260
  • 氨基酸序列
    MEMKKKINME LKNRAPEEVT ELVLDNCLCV NGEIEGLNDT FKELEFLSMA NVELSSLARL PSLNKLRKLE LSDNIISGGL EVLAEKCPNL TYLNLSGNKI KDLSTVEALQ NLKNLKSLDL FNCEITNLED YRESIFELLQ QITYLDGFDQ EDNEAPDSEE EDDDDEDGDE DEEDEDEDEA GPPEGYEEEE DDDEDEAGSE VGEGEEEVGL SYLMKDEIQD EEDDDDYVDE GEEEEEEEEE GLRGEKRKRD AEDDGEEDDD
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Histone chaperone that specifically mediates the genome-wide removal of histone H2A.Z/H2AZ1 from the nucleosome: removes H2A.Z/H2AZ1 from its normal sites of deposition, especially from enhancer and insulator regions. Not involved in deposition of H2A.Z/H2AZ1 in the nucleosome. May stabilize the evicted H2A.Z/H2AZ1-H2B dimer, thus shifting the equilibrium towards dissociation and the off-chromatin state. Inhibits activity of protein phosphatase 2A (PP2A). Does not inhibit protein phosphatase 1. May play a role in cerebellar development and synaptogenesis.
  • 基因功能参考文献：
    1. ANP32E gene mutations do not result in obvious motor activity defects. PMID: 23675506
    2. Cpd-1 null mice are viable and fertile, but display a subtle neurological clasping phenotype and mild motor deficits. PMID: 20844742
    3. This study propose that Anp32e/Cpd1 mediates synaptogenesis process by modulating Protein Phosphatase 2A activity. PMID: 16420440
  • 亚细胞定位：
    Cytoplasm. Nucleus.
  • 蛋白家族：
    ANP32 family
  • 组织特异性：
    Expressed at highest levels in cerebellum and spleen. In the cerebellum, expressed mainly in granule cells and, to a lesser extent, in Purkinje cells.
  • 数据库链接：

    KEGG: mmu:66471

    STRING: 10090.ENSMUSP00000128483

    UniGene: Mm.218657