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  4. Recombinant Mouse ADP-ribosylation factor-binding protein GGA2 (Gga2)

Recombinant Mouse ADP-ribosylation factor-binding protein GGA2 (Gga2)

  • 中文名称：
    小鼠Gga2重组蛋白
  • 货号：
    CSB-YP750808MO
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    小鼠Gga2重组蛋白
  • 货号：
    CSB-EP750808MO
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    小鼠Gga2重组蛋白
  • 货号：
    CSB-EP750808MO-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    小鼠Gga2重组蛋白
  • 货号：
    CSB-BP750808MO
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    小鼠Gga2重组蛋白
  • 货号：
    CSB-MP750808MO
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    Gga2
  • Uniprot No.：
  • 别名：
    Gga2; Kiaa1080ADP-ribosylation factor-binding protein GGA2; Gamma-adaptin-related protein 2; Golgi-localized; gamma ear-containing; ARF-binding protein 2
  • 种属：
    Mus musculus (Mouse)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-603
  • 氨基酸序列
    MAATAVAAGT GSPAGTESAE GGPGAAAALE LWLNKATDPS MAEQDWSAIQ KFCEQVNTDP SGPTHAPWLL AHKIQSPQEK EALYALTVLE ICMNHCGEKF HSEVAKFRFL NELIKVLSPK YLGAWATEKV KGRVIEILFS WTVWFPEDIK IRDAYQMLKK QGIIKQDPKL PMDKILPPPS PWPKSIFDAD EEKSKLLTRL LKSNHPEDLQ AANRLIKNLV KEEQEKSEKV SRRVSAVEEV RSHVRVLREM LSMYRRPGHA LPDQQALQVV YERCEKLRPT LFRLASDTTD DDDALAEILQ ANDLLTQGVR LYKQVVEGRV SAGNAVPAAV GAIPAPRAFP NPEPCGLNCP LIDLETPSLL HQDLAALGIN DVPTRNQVVI PSCCNDKKQP GAITLMGGGI QSLSADRNLL DLFSPQPSPG LNYVPQKSIP KEVPPGTKAS PGWSWEAGPL ASSTASQNTP LAHVFVPLES VKPSSLPPIV VYDRNGFRIL LHFSQTGAPG HPDVKVLLLT MMSTATQPVW DVMFQVAVPK SMRVKLQPAS SSKLPAFSPL MPPAVISQTL LLDNPHKEPI RLRYKLTFNQ GGQPFSEVGE VKDFPDLAVL STA
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Plays a role in protein sorting and trafficking between the trans-Golgi network (TGN) and endosomes. Mediates the ARF-dependent recruitment of clathrin to the TGN and binds ubiquitinated proteins and membrane cargo molecules with a cytosolic acidic cluster-dileucine (DXXLL) motif. Mediates export of the GPCR receptor ADRA2B to the cell surface. Regulates retrograde transport of phosphorylated form of BACE1 from endosomes to the trans-Golgi network.
  • 基因功能参考文献：
    1. GGA2 binds to the internal DXXLL motif of the LRP9 PMID: 22762444
  • 亚细胞定位：
    Golgi apparatus, trans-Golgi network membrane; Peripheral membrane protein. Endosome membrane; Peripheral membrane protein. Early endosome membrane; Peripheral membrane protein.
  • 蛋白家族：
    GGA protein family
  • 数据库链接：

    KEGG: mmu:74105

    STRING: 10090.ENSMUSP00000033160

    UniGene: Mm.29619