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  4. Recombinant Mouse 40S ribosomal protein S19 (Rps19)

Recombinant Mouse 40S ribosomal protein S19 (Rps19)

  • 中文名称：
    小鼠Rps19重组蛋白
  • 货号：
    CSB-YP880458MO
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    小鼠Rps19重组蛋白
  • 货号：
    CSB-EP880458MO
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    小鼠Rps19重组蛋白
  • 货号：
    CSB-EP880458MO-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    小鼠Rps19重组蛋白
  • 货号：
    CSB-BP880458MO
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    小鼠Rps19重组蛋白
  • 货号：
    CSB-MP880458MO
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    Rps19
  • Uniprot No.：
  • 别名：
    Rps19; 40S ribosomal protein S19
  • 种属：
    Mus musculus (Mouse)
  • 蛋白长度：
    Full Length of Mature Protein
  • 表达区域：
    2-145
  • 氨基酸序列
    PGVTVKDVN QQEFVRALAA FLKKSGKLKV PEWVDTVKLA KHKELAPYDE NWFYTRAAST ARHLYLRGGA GVGSMTKIYG GRQRNGVRPS HFSRGSKSVA RRVLQALEGL KMVEKDQDGG RKLTPQGQRD LDRIAGQVAA ANKKH
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Required for pre-rRNA processing and maturation of 40S ribosomal subunits.
  • 基因功能参考文献：
    1. Mutation of the key residue for extraribosomal function of ribosomal protein S19 cause increased grooming behaviors in mice. Results suggest an involvement of RP S19 oligomers in some anxiety-like behavior, especially grooming behavior. PMID: 27424793
    2. Rps19 mutant shows behavioural phenotypes resembling that of the human Diamond-Blackfan anaemia syndrome. PMID: 27643579
    3. indicate the importance of the RP S19 oligomer-induced macrophage recruitment in coagulum resorption PMID: 25329761
    4. Rps19 mutant embryonic stem cells showed significant increase in p53 protein expression. PMID: 24558476
    5. We report the generation of mouse models for RPS19-deficient Diamond Blackfan anemia using transgenic RNA interference that allows an inducible and graded down-regulation of Rps19. PMID: 21989989
    6. generated a transgenic model expressing an RPS19 mutation in which an arginine residue is replaced with a tryptophan residue at codon 62 as a model of Diamond-Blackfan anemia PMID: 20606162
    7. RPS19 mRNA and protein expression were shown to decrease during terminal erythroid differentiation. PMID: 12393682
    8. Results indicate that ribosomal protein S19 (-/-) zygotes do not form blastocysts, whereas one normal Rps19 allele in mice is sufficient to maintain normal ribosomal and possibly extraribosomal functions. PMID: 15082795
    9. presence of an RP S19 dimer- and C5a receptor-mediated autocrine-type augmentation mechanism during Mn II-induced apoptosis in the mouse fibroblastic cell line PMID: 15543555
    10. the loss of one Rps19 allele in mice is fully compensated for at the transcriptional level with preservation of erythropoiesis PMID: 16458028
    11. Study reports two mouse dark skin (Dsk) loci caused by mutations in Rps19 (ribosomal protein S19) and Rps20 (ribosomal protein S20). PMID: 18641651

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  • 蛋白家族：
    Eukaryotic ribosomal protein eS19 family
  • 数据库链接：

    KEGG: mmu:20085

    STRING: 10090.ENSMUSP00000104067

    UniGene: Mm.300281