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  4. Recombinant Human herpesvirus 1 Tegument protein UL14 (UL14)

Recombinant Human herpesvirus 1 Tegument protein UL14 (UL14)

  • 中文名称：
    Recombinant Human herpesvirus 1 Tegument protein UL14 (UL14),Yeast
  • 货号：
    CSB-YP366129HWY
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    Recombinant Human herpesvirus 1 Tegument protein UL14 (UL14),Yeast
  • 货号：
    CSB-EP366129HWY
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    Recombinant Human herpesvirus 1 Tegument protein UL14 (UL14),Yeast
  • 货号：
    CSB-EP366129HWY-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    Recombinant Human herpesvirus 1 Tegument protein UL14 (UL14),Yeast
  • 货号：
    CSB-BP366129HWY
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    Recombinant Human herpesvirus 1 Tegument protein UL14 (UL14),Yeast
  • 货号：
    CSB-MP366129HWY
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    UL14
  • Uniprot No.：
  • 别名：
    UL14; Tegument protein UL14
  • 种属：
    Human herpesvirus 1 (strain 17) (HHV-1) (Human herpes simplex virus 1)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-219
  • 氨基酸序列
    MDRDAAHAAL RRRLAETHLR AEIYKDQTLQ LHREGVSTQD PRFVGAFMAA KAAHLELEAR LKSRARLEMM RQRATCVKIR VEEQAARRDF LTAHRRYLDP ALGERLDAVD DRLADQEEQL EEAATNASLW GDGDLAEGWM SPADSDLLVM WQLTSAPKVH ANGPSRIGSH PTYTPTPTGP PGAPAAPLSR TPPSPAPPTG PATDPASASG FARDYPDGE
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Contributes to the nuclear transport of the viral transcriptional activator VP16 during the early phase of infection. Therefore, participates indirectly in the regulation of the immediate-early gene expression. Additionally, seems to be important for efficient nuclear targeting of capsids. The UL51-UL14 complex regulates final viral envelopment for efficient viral replication.
  • 基因功能参考文献：
    1. UL51 amino acid residues Leu-111, Ile-119, and Tyr-123 were required for interaction with UL14 in herpes simplex virus 1-infected cells and the UL51-UL14 complex regulated final viral envelopment for efficient viral replication. PMID: 27440890
    2. By constructing a series of deletion mutants fused with enhanced yellow fluorescent protein (EYFP), the nuclear export signals of UL4 were for the first time mapped to amino acid residues 178 to 186. PMID: 21979574
    3. UL14 interacts with cellular factor TSC22D3 during replication. PMID: 21512757
    4. UL14 (i) enhanced VP16 nuclear localization at the immediately early phase, thus indirectly regulating the expression of immediate-early genes, and (ii) was associated with efficient nuclear targeting of capsids. PMID: 18032514
  • 亚细胞定位：
    Virion tegument. Host cytoplasm. Host nucleus.
  • 蛋白家族：
    Alphaherpesvirinae HHV-1 UL14 protein family
  • 数据库链接：

    KEGG: vg:2703384