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  4. Recombinant Human herpesvirus 1 Capsid protein VP26 (UL35)

Recombinant Human herpesvirus 1 Capsid protein VP26 (UL35)

  • 货号：
    CSB-YP320623HWY
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 货号：
    CSB-EP320623HWY
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 货号：
    CSB-EP320623HWY-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 货号：
    CSB-BP320623HWY
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 货号：
    CSB-MP320623HWY
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    SCP
  • Uniprot No.：
  • 别名：
    SCP; UL35; Small capsomere-interacting protein
  • 种属：
    Human herpesvirus 1 (strain 17) (HHV-1) (Human herpes simplex virus 1)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-112
  • 氨基酸序列
    MAVPQFHRPS TVTTDSVRAL GMRGLVLATN NSQFIMDNNH PHPQGTQGAV REFLRGQAAA LTDLGLAHAN NTFTPQPMFA GDAPAAWLRP AFGLRRTYSP FVVREPSTPG TP
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Participates in the assembly of the infectious particles by decorating the outer surface of the capsid shell and thus forming a layer between the capsid and the tegument. Complexes composed of the major capsid protein and small capsomere-interacting protein/SCP assemble together in the host cytoplasm and are translocated to the nucleus, where they accumulate and participate in capsid assembly. Interaction with host dynein light chains suggests a possible function in the retrogarde transport of incoming viral capsids.
  • 基因功能参考文献：
    1. Collectively, these results indicated that VP26 was required for efficient viral DNA packaging and proper localization of nuclear capsids. PMID: 28679756
    2. s postulate that phosphorylation of VP26 at Thr-111 regulates VP26 function in vitro and in vivo. PMID: 25810545
    3. The N-terminal half of pUL35, in particular residues 30-43, was identified as a common region for the binding of DYNLT1 and DYNLT3. PMID: 20668116
    4. The interaction of VP26 with tetraspanin-7 plays an essential role in normal HSV-1 replication. PMID: 20630051
    5. These data suggest that besides VP26, HSV-1 encodes other receptors for dynein or dynactin. PMID: 16873277

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  • 亚细胞定位：
    Virion. Host nucleus.
  • 蛋白家族：
    Herpesviridae small capsomere-interacting protein family
  • 数据库链接：

    KEGG: vg:2703356