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  4. Recombinant Human cytomegalovirus Uracil-DNA glycosylase (UL114)

Recombinant Human cytomegalovirus Uracil-DNA glycosylase (UL114)

  • 中文名称：
    Recombinant Human cytomegalovirus Uracil-DNA glycosylase(UL114),Yeast
  • 货号：
    CSB-YP025641HWW
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    Recombinant Human cytomegalovirus Uracil-DNA glycosylase(UL114),Yeast
  • 货号：
    CSB-EP025641HWW
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    Recombinant Human cytomegalovirus Uracil-DNA glycosylase(UL114),Yeast
  • 货号：
    CSB-EP025641HWW-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    Recombinant Human cytomegalovirus Uracil-DNA glycosylase(UL114),Yeast
  • 货号：
    CSB-BP025641HWW
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    Recombinant Human cytomegalovirus Uracil-DNA glycosylase(UL114),Yeast
  • 货号：
    CSB-MP025641HWW
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    UL114
  • Uniprot No.：
  • 别名：
    UL114Uracil-DNA glycosylase; UDG; EC 3.2.2.27; UNG
  • 种属：
    Human cytomegalovirus (strain Merlin) (HHV-5) (Human herpesvirus 5)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-250
  • 氨基酸序列
    MALKQWMLAN IADNKGSLLT PDEQARVFCL SADWIRFLSL PDHDTVLLRD TVAAVEGARQ LEMVYPAPEH VHRWSYLCPP EQVRVVIVGQ DPYCDGSASG LAFGTLAGRP PPPSLNNVFR ELARTVDGFQ RPASGCLDAW ARRGVLLLNT VFTVVHGQPG SHRHLGWQTL SNHVIRRLSE RREHLVFMLW GADAHTCEYL IDRRRHLVLK SCHPSPRNTT RAFVGNDHFI LANAYLDTHY RETMDWRLCG
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or deamination of cytosines. Therefore may reduce deleterious uracil incorporation into the viral genome, particularly in terminally differentiated cells which lack DNA repair enzymes.
  • 基因功能参考文献：
    1. Data demonstrated a catalytically inefficient viral uracil DNA glycosylase that was highly enriched in viral replication foci, thus supporting an important role of UL114 in replication rather than repair of the viral genome. PMID: 18599070
  • 亚细胞定位：
    Host nucleus.
  • 蛋白家族：
    Uracil-DNA glycosylase (UDG) superfamily, UNG family
  • 数据库链接：

    KEGG: vg:3077539