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  4. Recombinant Human Zinc finger FYVE domain-containing protein 21 (ZFYVE21)

Recombinant Human Zinc finger FYVE domain-containing protein 21 (ZFYVE21)

  • 中文名称：
    人ZFYVE21重组蛋白
  • 货号：
    CSB-YP859829HU
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    人ZFYVE21重组蛋白
  • 货号：
    CSB-EP859829HU
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    人ZFYVE21重组蛋白
  • 货号：
    CSB-EP859829HU-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    人ZFYVE21重组蛋白
  • 货号：
    CSB-BP859829HU
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    人ZFYVE21重组蛋白
  • 货号：
    CSB-MP859829HU
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    ZFYVE21
  • Uniprot No.：
  • 别名：
    1110013H04Rik; AW558780; C85416; FYVE domain containing 21; MGC2550; ZF21; ZFY21_HUMAN; ZFYVE 21; ZFYVE21; Zinc finger FYVE domain containing 21; Zinc finger FYVE domain containing protein 21; Zinc finger FYVE domain-containing protein 21
  • 种属：
    Homo sapiens (Human)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-234
  • 氨基酸序列
    MSSEVSARRD AKKLVRSPSG LRMVPEHRAF GSPFGLEEPQ WVPDKECRRC MQCDAKFDFL TRKHHCRRCG KCFCDRCCSQ KVPLRRMCFV DPVRQCAECA LVSLKEAEFY DKQLKVLLSG ATFLVTFGNS EKPETMTCRL SNNQRYLFLD GDSHYEIEIV HISTVQILTE GFPPGGGNAR ATGMFLQYTV PGTEGVTQLK LTVVEDVTVG RRQAVAWLVA MHKAAKLLYE SRDQ
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Plays a role in cell adhesion, and thereby in cell motility which requires repeated formation and disassembly of focal adhesions. Regulates microtubule-induced PTK2/FAK1 dephosphorylation, an event important for focal adhesion disassembly, as well as integrin beta-1/ITGB1 cell surface expression.
  • 基因功能参考文献：
    1. this study demonstrates that ZF21 is a key player regulating multiple aspects of cancer cell migration and invasion. PMID: 23382803
    2. the C-terminal region is important for the ability of ZF21 to induce disassembly of FAs and cell migration PMID: 21768110
    3. ZF21 is a new regulator of focal adhesion disassembly and a potential member of the spreading initiation center. We identified 45 proteins including FA-related proteins and multiple RNA binding proteins PMID: 20890123
  • 亚细胞定位：
    Cell junction, focal adhesion. Cytoplasmic vesicle. Endosome. Note=Within cytoplasmic vesicles, partially colocalizes with EEA1, an endosomal marker.
  • 数据库链接：

    HGNC: 20760

    OMIM: 613504

    KEGG: hsa:79038

    UniGene: Hs.592322