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Recombinant Human Myeloid-derived growth factor (MYDGF)

  • 中文名称：
    人MYDGF重组蛋白
  • 货号：
    CSB-YP842625HU
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    人MYDGF重组蛋白
  • 货号：
    CSB-EP842625HU
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    人MYDGF重组蛋白
  • 货号：
    CSB-EP842625HU-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    人MYDGF重组蛋白
  • 货号：
    CSB-BP842625HU
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    人MYDGF重组蛋白
  • 货号：
    CSB-MP842625HU
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    MYDGF
  • Uniprot No.：
  • 别名：
    C19orf10; Chromosome 19 open reading frame 10; CS010_HUMAN; EUROIMAGE1875335; IL 25; IL 27; IL-25; IL25; IL27; IL27w; Interleukin 25; Interleukin 27 working designation ; Interleukin-25; Interleukin25; R33729 1; R337291; SF20 ; Stromal cell derived growth factor; Stromal cell derived growth factor SF20; Stromal cell-derived growth factor SF20; Uncharacterized protein C19orf10 precursor; UPF0556 protein C19orf10
  • 种属：
    Homo sapiens (Human)
  • 蛋白长度：
    Full Length of Mature Protein
  • 表达区域：
    32-173
  • 氨基酸序列
    VSEPTTVAF DVRPGGVVHS FSHNVGPGDK YTCMFTYASQ GGTNEQWQMS LGTSEDHQHF TCTIWRPQGK SYLYFTQFKA EVRGAEIEYA MAYSKAAFER ESDVPLKTEE FEVTKTAVAH RPGAFKAELS KLVIVAKASR TEL
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Bone marrow-derived monocyte and paracrine-acting protein that promotes cardiac myocyte survival and adaptive angiogenesis for cardiac protection and/or repair after myocardial infarction (MI). Stimulates endothelial cell proliferation through a MAPK1/3-, STAT3- and CCND1-mediated signaling pathway. Inhibits cardiac myocyte apoptosis in a PI3K/AKT-dependent signaling pathway. Involved in endothelial cell proliferation and angiogenesis.
  • 基因功能参考文献：
    1. Bone marrow-derived monocytes and macrophages produce this protein endogenously to protect and repair the heart after myocardial infarction. PMID: 25581518
    2. Taken together, these data suggest that c19orf10 might be one of the growth factors and potential molecular targets activated in HCC. PMID: 21128247
    3. we identified a novel protein, c19orf10 (chromosome 19 open reading frame 10), produced by fibroblast-like synoviocytes PMID: 17362502
  • 亚细胞定位：
    Secreted. Endoplasmic reticulum-Golgi intermediate compartment. Endoplasmic reticulum. Golgi apparatus.
  • 蛋白家族：
    MYDGF family
  • 组织特异性：
    Expressed in eosinophils (at protein level). Expressed in bone marrow cells. Expressed in synovial tissue. Found in synovial fluid of patients with arthropaties.
  • 数据库链接：

    HGNC: 16948

    OMIM: 606746

    KEGG: hsa:56005

    STRING: 9606.ENSP00000262947

    UniGene: Hs.465645