Your Good Partner in Biology Research

  1. 首页
  2. 蛋白
  3. 重组蛋白
  4. Recombinant Human Transmembrane gamma-carboxyglutamic acid protein 4 (PRRG4), partial

Recombinant Human Transmembrane gamma-carboxyglutamic acid protein 4 (PRRG4), partial

  • 中文名称：
    人PRRG4重组蛋白
  • 货号：
    CSB-YP874853HU
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    人PRRG4重组蛋白
  • 货号：
    CSB-EP874853HU
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    人PRRG4重组蛋白
  • 货号：
    CSB-EP874853HU-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    人PRRG4重组蛋白
  • 货号：
    CSB-BP874853HU
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    人PRRG4重组蛋白
  • 货号：
    CSB-MP874853HU
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    PRRG4
  • Uniprot No.：
  • 别名：
    9930111I18Rik; MGC117538; Proline-rich gamma-carboxyglutamic acid protein 4; Proline-rich Gla protein 4; PRRG 4; PRRG4; TMG4; TMG4_HUMAN; Transmembrane gamma-carboxyglutamic acid protein 4
  • 种属：
    Homo sapiens (Human)
  • 蛋白长度：
    Partial
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    May control axon guidance across the CNS. Prevents the delivery of ROBO1 at the cell surface and downregulates its expression.
  • 基因功能参考文献：
    1. PRRG4 could re-localize hRobo1 from the cell surface, suggesting that PRRG4 is a functional homologue of Comm. Comm is required for axon guidance and synapse formation in the fly, so PRRG4 could contribute to the autistic symptoms of WAGR by disturbing either of these processes in the developing human brain. PMID: 28859078
    2. the unique genotype identified in this study suggested that haploinsufficiencies of PAX6 or PRRG4 included in this region are candidate genes for severe developmental delay and autistic features characteristic of WAGR syndrome. PMID: 24357251
    3. Cellular localization and characterization of cytosolic binding partners for Gla domain-containing proteins PRRG4 and PRRG2. PMID: 23873930
  • 亚细胞定位：
    Endoplasmic reticulum-Golgi intermediate compartment membrane; Single-pass type I membrane protein. Cell membrane; Single-pass type I membrane protein.
  • 组织特异性：
    Widely expressed with highest levels in kidney.
  • 数据库链接：

    HGNC: 30799

    OMIM: 611690

    KEGG: hsa:79056

    STRING: 9606.ENSP00000257836

    UniGene: Hs.471695