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  4. Recombinant Human Thioredoxin domain-containing protein 2 (TXNDC2)

Recombinant Human Thioredoxin domain-containing protein 2 (TXNDC2)

  • 中文名称：
    人TXNDC2重组蛋白
  • 货号：
    CSB-YP771449HU
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    人TXNDC2重组蛋白
  • 货号：
    CSB-EP771449HU
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    人TXNDC2重组蛋白
  • 货号：
    CSB-EP771449HU-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    人TXNDC2重组蛋白
  • 货号：
    CSB-BP771449HU
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    人TXNDC2重组蛋白
  • 货号：
    CSB-MP771449HU
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    TXNDC2
  • Uniprot No.：
  • 别名：
    TXNDC2; SPTRX; SPTRX1; Thioredoxin domain-containing protein 2; Spermatid-specific thioredoxin-1; Sptrx-1
  • 种属：
    Homo sapiens (Human)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-553
  • 氨基酸序列
    MDVDKELGME SVKAGASGKP EMRLGTQEET SEGDANESSL LVLSSNVPLL ALEFLEIAQA KEKAFLPMVS HTFHMRTEES DASQEGDDLP KSSANTSHPK QDDSPKSSEE TIQPKEGDIP KAPEETIQSK KEDLPKSSEK AIQPKESNIP KSSAKPIQPK LGNIPKASVK PSQPKEGDIP KAPEETIQSK KEDLPKSSEE AIQPKEGDIP KSSAKPIQPK LGNIAKTSVK PSQPKESDIP KSPEETIQPK EGDIPKSSAK PIQPKLGNIP KASVKPSQPK EGDISKSPEE AIQPKEGDLP KSLEEAIQPK EGDIPKSPEE AIQPKEGDIP KSLEEAIQPK EGDIPKSPEE TIQPKKGDIP KSPEEAIQPK EGDIPKSPKQ AIQPKEGDIP KSLEEAIPPK EIDIPKSPEE TIQPKEDDSP KSLEEATPSK EGDILKPEEE TMEFPEGDKV KVILSKEDFE ASLKEAGERL VAVDFSATWC GPCRTIRPFF HALSVKHEDV VFLEVDADNC EEVVRECAIM CVPTFQFYKK EEKVDELCGA LKEKLEAVIA ELK
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Probably plays a regulatory role in sperm development. May participate in regulation of fibrous sheath (FS) assembly by supporting the formation of disulfide bonds during sperm tail morphogenesis. May also be required to rectify incorrect disulfide pairing and generate suitable pairs between the FS constituents. Can reduce disulfide bonds in vitro in the presence of NADP and thioredoxin reductase.
  • 基因功能参考文献：
    1. The patients with advanced-stagemalignant pleural mesothelioma (MPM) showed higher levels of TRX than those with early-stage MPM. PMID: 21375472
    2. sperm specific expression, together with chromosomal assignment to a position as a potential locus for flagellar anomalies and male infertility phenotypes, suggests that it might be a novel component of the human sperm axonemal organization. PMID: 11737268
    3. spermatid-specific thioredoxin-1 (Sptrx-1) is a two-domain protein with oxidizing activity PMID: 12387870
  • 亚细胞定位：
    Cytoplasm. Note=In ejaculated spermatozoa, it localizes in the caudal region of the head to the end of the principal piece.
  • 组织特异性：
    Testis-specific. Only expressed during spermiogenesis, prominently in round and elongating spermatids.
  • 数据库链接：

    HGNC: 16470

    OMIM: 617790

    KEGG: hsa:84203

    STRING: 9606.ENSP00000304908

    UniGene: Hs.98712