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  4. Recombinant Human Sterile alpha motif domain-containing protein 11 (SAMD11)

Recombinant Human Sterile alpha motif domain-containing protein 11 (SAMD11)

  • 中文名称：
    人SAMD11重组蛋白
  • 货号：
    CSB-YP836271HU
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    人SAMD11重组蛋白
  • 货号：
    CSB-EP836271HU
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    人SAMD11重组蛋白
  • 货号：
    CSB-EP836271HU-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    人SAMD11重组蛋白
  • 货号：
    CSB-BP836271HU
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    人SAMD11重组蛋白
  • 货号：
    CSB-MP836271HU
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    SAMD11
  • Uniprot No.：
  • 别名：
    SAMD11; Sterile alpha motif domain-containing protein 11; SAM domain-containing protein 11
  • 种属：
    Homo sapiens (Human)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-681
  • 氨基酸序列
    MSKGILQVHP PICDCPGCRI SSPVNRGRLA DKRTVALPAA RNLKKERTPS FSASDGDSDG SGPTCGRRPG LKQEDGPHIR IMKRRVHTHW DVNISFREAS CSQDGNLPTL ISSVHRSRHL VMPEHQSRCE FQRGSLEIGL RPAGDLLGKR LGRSPRISSD CFSEKRARSE SPQEALLLPR ELGPSMAPED HYRRLVSALS EASTFEDPQR LYHLGLPSHG EDPPWHDPPH HLPSHDLLRV RQEVAAAALR GPSGLEAHLP SSTAGQRRKQ GLAQHREGAA PAAAPSFSER ELPQPPPLLS PQNAPHVALG PHLRPPFLGV PSALCQTPGY GFLPPAQAEM FAWQQELLRK QNLARLELPA DLLRQKELES ARPQLLAPET ALRPNDGAEE LQRRGALLVL NHGAAPLLAL PPQGPPGSGP PTPSRDSARR APRKGGPGPA SARPSESKEM TGARLWAQDG SEDEPPKDSD GEDPETAAVG CRGPTPGQAP AGGAGAEGKG LFPGSTLPLG FPYAVSPYFH TGAVGGLSMD GEEAPAPEDV TKWTVDDVCS FVGGLSGCGE YTRVFREQGI DGETLPLLTE EHLLTNMGLK LGPALKIRAQ VARRLGRVFY VASFPVALPL QPPTLRAPER ELGTGEQPLS PTTATSPYGG GHALAGQTSP KQENGTLALL PGAPDPSQPL C
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    May play a role in photoreceptor development.
  • 基因功能参考文献：
    1. analysis of a homozygous nonsense mutation in SAMD11 in five individuals diagnosed with adult-onset retinitis pigmentosa; SAMD11 interacts with CRX and is expressed in retina PMID: 27734943
    2. SEZ6L, HISPPD1, FEZF1, SAMD11 gene variants may be associated with autism spectrum disorder. PMID: 26204995
    3. SAMD11 was found to be widely expressed in many cell lines and ocular tissues and its transcription was not regulated by CRX, OTX2 or NR2E3 proteins. PMID: 23978614
  • 亚细胞定位：
    Nucleus.
  • 数据库链接：

    HGNC: 28706

    KEGG: hsa:148398

    UniGene: Hs.335293