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  4. Recombinant Human Spermatogenesis-associated protein 4 (SPATA4)

Recombinant Human Spermatogenesis-associated protein 4 (SPATA4)

  • 中文名称：
    人SPATA4重组蛋白
  • 货号：
    CSB-YP850876HU
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    人SPATA4重组蛋白
  • 货号：
    CSB-EP850876HU
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    人SPATA4重组蛋白
  • 货号：
    CSB-EP850876HU-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    人SPATA4重组蛋白
  • 货号：
    CSB-BP850876HU
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    人SPATA4重组蛋白
  • 货号：
    CSB-MP850876HU
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    SPATA4
  • Uniprot No.：
  • 别名：
    SPATA4; TSARG2; Spermatogenesis-associated protein 4; Testis and spermatogenesis cell-related protein 2; Testis spermatocyte apoptosis-related gene 2 protein
  • 种属：
    Homo sapiens (Human)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-305
  • 氨基酸序列
    MAAAGQEKGY LTQTAAALDK SPSLSPQLAA PIRGRPKKCL VYPHAPKSSR LSRSVLRWLQ GLDLSFFPRN INRDFSNGFL IAEIFCIYYP WELELSSFEN GTSLKVKLDN WAQLEKFLAR KKFKLPKELI HGTIHCKAGV PEILIEEVYT LLTHREIKSI QDDFVNFTDY SYQMRLPLVS RSTVSKSIKD NIRLSELLSN PNMLTNELKA EFLILLHMLQ RKLGRKLNPE WFDVKPTVGE VTLNHLPAQA SGRRYNLKVK RGRVVPVLPN IGSGGSSHRE IHVKQAGQHS YYSAMKPIRN MDKKP
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    May play a role in apoptosis regulation.
  • 基因功能参考文献：
    1. SPATA4 protects HeLa cells against etoposide-induced apoptosis through the mitochondrial apoptotic pathway, providing further evidence that SPATA4 plays a role in regulating apoptosis PMID: 26424010
    2. Results suggest a role for SPATA4 in membrane traffic and a specialized function for TRAPP in spermatocytes. PMID: 21827752
    3. expressed in many tissues and mapped to chromosome 4q33-34.1 by database analyses PMID: 12019456
    4. TSARG2 may play an important role in the development of cryptorchid testis and be a testis-specific apoptosis candidate oncogene PMID: 15158438
    5. analysis of SPATA4 expression and variation in promotor sequences PMID: 16336790

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  • 亚细胞定位：
    Nucleus.
  • 组织特异性：
    Highly expressed in testis, the expression is observed precisely in seminiferous tubules.
  • 数据库链接：

    HGNC: 17333

    OMIM: 609879

    KEGG: hsa:132851

    STRING: 9606.ENSP00000280191

    UniGene: Hs.481235