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  4. Recombinant Human Rhomboid domain-containing protein 2 (RHBDD2), partial

Recombinant Human Rhomboid domain-containing protein 2 (RHBDD2), partial

  • 中文名称：
    人RHBDD2重组蛋白
  • 货号：
    CSB-YP743985HU1
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    人RHBDD2重组蛋白
  • 货号：
    CSB-EP743985HU1
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    人RHBDD2重组蛋白
  • 货号：
    CSB-EP743985HU1-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    人RHBDD2重组蛋白
  • 货号：
    CSB-BP743985HU1
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    人RHBDD2重组蛋白
  • 货号：
    CSB-MP743985HU1
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    RHBDD2
  • Uniprot No.：
  • 别名：
    RHBDD2; RHBDL7; Rhomboid domain-containing protein 2
  • 种属：
    Homo sapiens (Human)
  • 蛋白长度：
    Partial
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 基因功能参考文献：
    1. The RHBDD2 subcellular localization was corroborated at the Golgi apparatus. PMID: 29901166
    2. RHBDD2 overexpression in breast cancer could represent an adaptive phenotype to the stressful tumor microenvironment by modulating the endoplasmic reticulum stress response. PMID: 24078384
    3. Quantitative reverse transcription-polymerase chain reaction (RT-PCR) analysis showed a significant RHBDD2 mRNA overexpression in advanced breast cancer compared with normal tissue samples (p = 0.012). PMID: 24185965
    4. RHBDD2 protein plays important roles in the development and normal function of the retina PMID: 23386608
    5. Increased RHBDD2 expression in response to the chemotherapy is associated with advanced stages of colorectal cancer. PMID: 22965880
    6. RHBDD2 over-expression behaves as an indicator of poor prognosis and may play a role facilitating breast cancer progression. PMID: 19616622

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  • 亚细胞定位：
    Golgi apparatus, cis-Golgi network membrane; Multi-pass membrane protein.
  • 蛋白家族：
    Peptidase S54 family
  • 数据库链接：

    HGNC: 23082

    OMIM: 615203

    KEGG: hsa:57414

    STRING: 9606.ENSP00000006777

    UniGene: Hs.488827