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  4. Recombinant Human Regenerating islet-derived protein 3-gamma (REG3G)

Recombinant Human Regenerating islet-derived protein 3-gamma (REG3G)

  • 中文名称：
    人REG3G重组蛋白
  • 货号：
    CSB-YP751009HU
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    人REG3G重组蛋白
  • 货号：
    CSB-EP751009HU-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    人REG3G重组蛋白
  • 货号：
    CSB-BP751009HU
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    人REG3G重组蛋白
  • 货号：
    CSB-MP751009HU
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    REG3G
  • Uniprot No.：
  • 别名：
    LPPM429; Pancreatitis-associated protein 1B; Pancreatitis-associated protein IB; PAP IB; PAP-1B; PAP1B; PAPIB; REG III; Reg III-gamma; REG-3-gamma; REG3G; REG3G_HUMAN; Regenerating islet derived 3 gamma; Regenerating islet-derived protein 3-gamma; Regenerating islet-derived protein III-gamma; UNQ429
  • 种属：
    Homo sapiens (Human)
  • 蛋白长度：
    Full Length of Mature Protein
  • 表达区域：
    27-175
  • 氨基酸序列
    EETQ KELPSPRISC PKGSKAYGSP CYALFLSPKS WMDADLACQK RPSGKLVSVL SGAEGSFVSS LVRSISNSYS YIWIGLHDPT QGSEPDGDGW EWSSTDVMNY FAWEKNPSTI LNPGHCGSLS RSTGFLKWKD YNCDAKLPYV CKFKD
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Bactericidal C-type lectin which acts exclusively against Gram-positive bacteria and mediates bacterial killing by binding to surface-exposed carbohydrate moieties of peptidoglycan. Restricts bacterial colonization of the intestinal epithelial surface and consequently limits activation of adaptive immune responses by the microbiota. The uncleaved form has bacteriostatic activity, whereas the cleaved form has bactericidal activity against L.monocytogenes and methicillin-resistant S.aureus. Regulates keratinocyte proliferation and differentiation after skin injury.
  • 基因功能参考文献：
    1. This gene encodes a secreted peptide that displays antimicrobial activity against Gram-positive bacteria. PMID: 16931762
    2. a model of CagA-directed REG3gamma expression in gastric epithelial cells via activation of the IL-11/gp130/STAT3 pathway PMID: 22312430
    3. REG III was identified and expressed predominantly in pancreas and testis, but not in small intestine PMID: 15556304
    4. PAP IB represents a good example of duplication and divergence, probably with the acquisition of new functions, thus participating in the evolution of the protein repertoire. PMID: 15777617
  • 亚细胞定位：
    Secreted. Cytoplasm.
  • 组织特异性：
    Predominantly expressed in pancreas, where it may be restricted to exocrine pancreas. Moderate expression levels in testis and weak in heart, kidney and placenta.
  • 数据库链接：

    HGNC: 29595

    OMIM: 609933

    KEGG: hsa:130120

    STRING: 9606.ENSP00000272324

    UniGene: Hs.447084