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  4. Recombinant Human Ras-related protein Rab-15 (RAB15)

Recombinant Human Ras-related protein Rab-15 (RAB15)

  • 中文名称：
    人RAB15重组蛋白
  • 货号：
    CSB-YP019163HU
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    人RAB15重组蛋白
  • 货号：
    CSB-EP019163HU-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    人RAB15重组蛋白
  • 货号：
    CSB-BP019163HU
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    人RAB15重组蛋白
  • 货号：
    CSB-MP019163HU
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    RAB15
  • Uniprot No.：
  • 别名：
    Rab 15; RAB15; RAB15 member RAS onocogene family; RAB15, member RAS onocogene family; RAB15_HUMAN; Ras related protein Rab 15; Ras related protein Rab15; Ras-related protein Rab-15
  • 种属：
    Homo sapiens (Human)
  • 蛋白长度：
    Full length protein
  • 表达区域：
    1-212
  • 氨基酸序列
    MAKQYDVLFR LLLIGDSGVG KTCLLCRFTD NEFHSSHIST IGVDFKMKTI EVDGIKVRIQ IWDTAGQERY QTITKQYYRR AQGIFLVYDI SSERSYQHIM KWVSDVDEYA PEGVQKILIG NKADEEQKRQ VGREQGQQLA KEYGMDFYET SACTNLNIKE SFTRLTELVL QAHRKELEGL RMRASNELAL AELEEEEGKP EGPANSSKTC WC
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    May act in concert with RAB3A in regulating aspects of synaptic vesicle membrane flow within the nerve terminal.
  • 基因功能参考文献：
    1. identified 4 Rab15 isoforms, Rab15CN, Rab15AN1, Rab15AN2 and Rab15AN3 in neuroblastoma cells and demonstrated that Rab15 isoform balance was significantly decreased in spheres of neuroblastoma cells; study suggests Rab15 alternative splicing may serve as a biomarker to discriminate tumor-initiating cells (TICs) from non-TICs in neuroblastoma PMID: 22427180
    2. Rab15 expression correlates with retinoic acid-induced differentiation of neuroblastoma cells PMID: 21491086
    3. Observational study of gene-disease association. (HuGE Navigator) PMID: 19913121
    4. Observational study of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator) PMID: 20628086
    5. Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator) PMID: 20379614
    6. Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator) PMID: 19170196
    7. Rab15 effector protein is a binding partner for Rab15-GTP. PMID: 16195351
    8. Observational study of gene-disease association. (HuGE Navigator) PMID: 19773279
    9. Observational study of gene-disease association. (HuGE Navigator) PMID: 19692168
    10. Observational study of gene-disease association. (HuGE Navigator) PMID: 19625176
    11. Observational study of gene-disease association. (HuGE Navigator) PMID: 18676680

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  • 亚细胞定位：
    Cell membrane; Lipid-anchor; Cytoplasmic side.
  • 蛋白家族：
    Small GTPase superfamily, Rab family
  • 数据库链接：

    HGNC: 20150

    KEGG: hsa:376267

    UniGene: Hs.512492