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  4. Recombinant Human Protein RFT1 homolog (RFT1), partial

Recombinant Human Protein RFT1 homolog (RFT1), partial

  • 中文名称：
    人RFT1重组蛋白
  • 货号：
    CSB-YP846583HU
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    人RFT1重组蛋白
  • 货号：
    CSB-EP846583HU
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    人RFT1重组蛋白
  • 货号：
    CSB-EP846583HU-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    人RFT1重组蛋白
  • 货号：
    CSB-BP846583HU
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    人RFT1重组蛋白
  • 货号：
    CSB-MP846583HU
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    RFT1
  • Uniprot No.：
  • 别名：
    RFT1; Protein RFT1 homolog
  • 种属：
    Homo sapiens (Human)
  • 蛋白长度：
    Partial
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    May be involved in N-linked oligosaccharide assembly. May participate in the translocation of oligosaccharide from the cytoplasmic side to the lumenal side of the endoplasmic reticulum membrane.
  • 基因功能参考文献：
    1. showed that this patient was compound heterozygous for two mutations in the RFT1 gene: c.1325G>A (p.R442Q) and c.110G>T (p.R37L) PMID: 26892341
    2. Six patients with RFT1-CDG show sensorineural deafness as part of a severe neurological syndrome PMID: 19856127
    3. Identification of novel missense mutations in exon 12 of the RFT1 gene in adult siblings with congenital disorder of glycosylation (CDG) syndrome caused by RFT1 deficiency. PMID: 23111317
    4. RFT1 deficiency in both yeast and human cells leads to the accumulation of incomplete DolPP-GlcNAc(2)Man(5) and to a profound glycosylation disorder in humans. PMID: 18313027
  • 相关疾病：
    Congenital disorder of glycosylation 1N (CDG1N)
  • 亚细胞定位：
    Membrane; Multi-pass membrane protein.
  • 蛋白家族：
    RFT1 family
  • 数据库链接：

    HGNC: 30220

    OMIM: 611908

    KEGG: hsa:91869

    STRING: 9606.ENSP00000296292

    UniGene: Hs.631910