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  4. Recombinant Human Protein FAM210B (FAM210B), partial

Recombinant Human Protein FAM210B (FAM210B), partial

  • 中文名称：
    人FAM210B重组蛋白
  • 货号：
    CSB-YP850327HU1
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    人FAM210B重组蛋白
  • 货号：
    CSB-EP850327HU1
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    人FAM210B重组蛋白
  • 货号：
    CSB-EP850327HU1-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    人FAM210B重组蛋白
  • 货号：
    CSB-BP850327HU1
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    人FAM210B重组蛋白
  • 货号：
    CSB-MP850327HU1
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    FAM210B
  • Uniprot No.：
  • 别名：
    FAM210B; C20orf108; PSEC0265; Protein FAM210B, mitochondrial
  • 种属：
    Homo sapiens (Human)
  • 蛋白长度：
    Partial
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Plays a role in erythroid differentiation. Involved in cell proliferation and tumor cell growth suppression. Involved in the metabolic reprogramming of cancer cells in a PDK4-dependent manner.
  • 基因功能参考文献：
    1. it was found that low expression of FAM210B was significantly correlated with decreased survival and enhanced metastasis in vivo and in vitro, and the loss of FAM210B led to an increased mitochondrial respiratory capacity and reduced glycolysis through the downregulation of pyruvate dehydrogenase kinase 4 (PDK4). PMID: 28594398
    2. Both human and murine FAM210B are abundantly expressed in the later stages of erythroblast development. Moreover, the deduced amino acid sequence predicted that FAM210B is a membrane protein, and Western blot analysis demonstrated its mitochondrial localization. Loss-of-function analysis in erythroid cells suggested that FAM210B may be involved in erythroid differentiation. PMID: 26968549
  • 亚细胞定位：
    Mitochondrion. Mitochondrion outer membrane; Multi-pass membrane protein.
  • 蛋白家族：
    FAM210 family
  • 组织特异性：
    Expressed in late erythroblast differentiation stages. Underexpressed in ovarian cancer epithelia cells compared with normal human ovarian surface epithelia.
  • 数据库链接：

    HGNC: 16102

    KEGG: hsa:116151

    STRING: 9606.ENSP00000360437

    UniGene: Hs.143736