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  4. Recombinant Human Platelet factor 4 variant (PF4V1)

Recombinant Human Platelet factor 4 variant (PF4V1)

  • 中文名称：
    人PF4V1重组蛋白
  • 货号：
    CSB-YP017810HU
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    人PF4V1重组蛋白
  • 货号：
    CSB-EP017810HU
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    人PF4V1重组蛋白
  • 货号：
    CSB-EP017810HU-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    人PF4V1重组蛋白
  • 货号：
    CSB-BP017810HU
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    人PF4V1重组蛋白
  • 货号：
    CSB-MP017810HU
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
  • Uniprot No.：
  • 别名：
    PF4V1; CXCL4V1; SCYB4V1; Platelet factor 4 variant; C-X-C motif chemokine 4 variant; CXCL4L1; PF4alt; PF4var1) [Cleaved into: Platelet factor 4 variant(4-74); Platelet factor 4 variant(5-74); Platelet factor 4 variant(6-74)]
  • 种属：
    Homo sapiens (Human)
  • 蛋白长度：
    Full Length of Mature Protein
  • 表达区域：
    31-104
  • 氨基酸序列
    FARAEAEEDG DLQCLCVKTT SQVRPRHITS LEVIKAGPHC PTAQLIATLK NGRKICLDLQ ALLYKKIIKE HLES
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Inhibitor of angiogenesis. Inhibitor of endothelial cell chemotaxis (in vitro).
  • 基因功能参考文献：
    1. Fibstatin and CXCL4L1 cooperate to inhibit endothelial cell proliferation, migration and tubulogenesis in vitro. PMID: 23747987
    2. fibstatin and CXCL4L1 have cooperative roles in inhibition of tumor invasion in lymph nodes PMID: 23747987
    3. Structural insight into the novel functional properties of human CXCL4L1. PMID: 23536183
    4. PF-4var/CXCL4L1 predicts outcome in stable coronary artery disease patients with preserved left ventricular function PMID: 22384011
    5. both CXCR3A and CXCR3B are implicated in the chemotactic and vascular effects of CXCL4L1. PMID: 20980681

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  • 亚细胞定位：
    Secreted.
  • 蛋白家族：
    Intercrine alpha (chemokine CxC) family
  • 数据库链接：

    HGNC: 8862

    OMIM: 173461

    KEGG: hsa:5197

    STRING: 9606.ENSP00000226524

    UniGene: Hs.72933