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  4. Recombinant Human OCIA domain-containing protein 1 (OCIAD1)

Recombinant Human OCIA domain-containing protein 1 (OCIAD1)

  • 中文名称：
    人OCIAD1重组蛋白
  • 货号：
    CSB-YP882129HU
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    人OCIAD1重组蛋白
  • 货号：
    CSB-EP882129HU
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    人OCIAD1重组蛋白
  • 货号：
    CSB-EP882129HU-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    人OCIAD1重组蛋白
  • 货号：
    CSB-BP882129HU
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    人OCIAD1重组蛋白
  • 货号：
    CSB-MP882129HU
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    OCIAD1
  • Uniprot No.：
  • 别名：
    Asrij; FLJ20455; MGC111072 ; OCAD1_HUMAN; OCIA; OCIA domain containing 1; OCIA domain-containing protein 1; OCIAD1; Ovarian carcinoma immunoreactive antigen; TPA018
  • 种属：
    Homo sapiens (Human)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-245
  • 氨基酸序列
    MNGRADFREP NAEVPRPIPH IGPDYIPTEE ERRVFAECND ESFWFRSVPL AATSMLITQG LISKGILSSH PKYGSIPKLI LACIMGYFAG KLSYVKTCQE KFKKLENSPL GEALRSGQAR RSSPPGHYYQ KSKYDSSVSG QSSFVTSPAA DNIEMLPHYE PIPFSSSMNE SAPTGITDHI VQGPDPNLEE SPKRKNITYE ELRNKNRESY EVSLTQKTDP SVRPMHERVP KKEVKVNKYG DTWDE
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Maintains stem cell potency. Increases STAT3 phosphorylation and controls ERK phosphorylation. May act as a scaffold, increasing STAT3 recruitment onto endosomes. Involved in integrin-mediated cancer cell adhesion and colony formation in ovarian cancer.
  • 基因功能参考文献：
    1. Like OCIAD1, OCIAD2 is a cancer-related protein and its expression level increases during the course of malignant progression and is thought to be a very useful marker for evaluating the malignancy of ovarian mucinous tumors. PMID: 22726067
    2. OCIAD1 is a potential biomarker of thyroid carcinoma but had no significant additive effect on the risk of distant metastasis. PMID: 22081784
    3. This is the first study to indicate that OCIAD1 is a key player in generating ovarian cancer recurrence. PMID: 20515946
    4. Over-expressed in metastatic ovarian cancer. Effect of OCIAD1 on cell adhesion may be related to its function in ovarian cancer. Possibility of OCIAD1's role in tumor metastasis. PMID: 18328549
  • 亚细胞定位：
    Endosome.
  • 蛋白家族：
    OCIAD1 family
  • 组织特异性：
    Isoform 1 is highly expressed in many tissues, including testis, brain, placenta, ovary, prostate and mammary gland. Isoform 2 expression is restricted to the central nervous system including brain, cerebellum and spinal cord.
  • 数据库链接：

    HGNC: 16074

    KEGG: hsa:54940

    STRING: 9606.ENSP00000264312

    UniGene: Hs.518750